BAG2 抗体 (N-Term)
Quick Overview for BAG2 抗体 (N-Term) (ABIN3042900)
抗原
See all BAG2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1-14, N-Term
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原理
- Anti-BAG2 Antibody Picoband®
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序列
- MAQAKINAKA NEGR
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-BAG2 Antibody (ABIN3042900). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human BAG2, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG
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anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibody
BAG2 适用: 人, 大鼠, 小鼠, 犬, 斑马鱼, 兔, Cow, 豚鼠, 马 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) antibodyBAG2 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (AA 1-211) antibodyBAG2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (AA 1-211) antibodyBAG2 适用: 人 WB, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibodyVerified BAG2 适用: 人, Pig WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (AA 102-211) antibodyBAG2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E12 unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibodyBAG2 适用: 人, 大鼠, 小鼠, 犬, 斑马鱼, 兔, Pig, Cow, 豚鼠, 马, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) antibodyKO Validated BAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (C-Term) antibodyBAG2 适用: 人, 大鼠, 小鼠, 犬, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-BCL2-Associated Athanogene 2 (BAG2) (AA 148-176), (C-Term) antibodyBAG2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB34133 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Takayama S, Xie Z, Reed JC (Feb 1999). "An evolutionarily conserved family of Hsp70/Hsc70 Molecular chaperone regulators". J Biol Chem 274 (2): 781-6. "Entrez Gene: BAG2 BCL2-associated athanogene 2" -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
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别名
- BAG2
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背景
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Synonyms: BAG family molecular chaperone regulator 2,BAG-2,Bcl-2-associated athanogene 2,BAG2,
Tissue Specificity: Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus. .
Background: BAG family molecular chaperone regulator 2 is a protein that in humans is encoded by the BAG2 gene. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner. The functional antagonisms displayed between BAG family proteins and Hip suggest that a proper balance of these 2 types of protein is required for achieving optimal cycles of substrate binding and release required for inducting conformational changes in proteins, with Hip promoting peptide substrate binding by Hsc70/Hsp70 and BAG family proteins promoting dissociation.
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分子量
- 140-150 kDa
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UniProt
- O95816
抗原
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