DRD5 抗体 (C-Term)
Quick Overview for DRD5 抗体 (C-Term) (ABIN3042836)
抗原
See all DRD5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 388-407, C-Term
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原理
- Anti-Dopamine Receptor D5/DRD5 Antibody Picoband®
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序列
- LISYNQDTVF HREIAAAYVH
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Dopamine Receptor D5/DRD5 Antibody (ABIN3042836). Tested in WB applications. This antibody reacts with Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse Dopamine Receptor D5, different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids.
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亚型
- IgG
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anti-Dopamine Receptor D5 (DRD5) (AA 361-477) antibody
DRD5 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D5 (DRD5) (Internal Region) antibodyVerified DRD5 适用: 人 ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated
anti-Dopamine Receptor D5 (DRD5) (AA 323-477) antibodyDRD5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D5 (DRD5) (AA 199-211), (Extracellular) antibodyDRD5 适用: 大鼠 WB, IHC, IF, FACS, LCI 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D5 (DRD5) (AA 251-350) antibodyDRD5 适用: 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D5 (DRD5) (Cytoplasmic Domain) antibodyDRD5 适用: 人, 犬 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D5 (DRD5) (AA 421-456), (C-Term) antibodyDRD5 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB52763 unconjugated
anti-Dopamine Receptor D5 (DRD5) (Extracellular Domain) antibodyDRD5 适用: 人, 大鼠 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D5 (DRD5) (N-Term) antibodyDRD5 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Dopamine Receptor D5 (DRD5) (AA 19-56), (N-Term) antibodyDRD5 适用: 小鼠 WB 宿主: 兔 Polyclonal RB52770 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Mouse, Rat
1. Li, H., Armando, I., Yu, P., Escano, C., Mueller, S. C., Asico, L., Pascua, A., Lu, Q., Wang, X., Villar, V. A. M., Jones, J. E., Wang, Z., and 9 others. Dopamine 5 receptor mediates Ang II type 1 receptor degradation via a ubiquitin-proteasome pathway in mice and human cells. J. Clin. Invest. 118: 2180-2189, 2008. Note: Erratum: J. Clin. Invest. 118: 2986 only, 2008. 2. Lowe, N., Kirley, A., Hawi, Z., Sham, P., Wickham, H., Kratochvil, C. J., Smith, S. D., Lee, S. Y., Levy, F., Kent, L., Middle, F., Rohde, L. A., and 20 others. Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes. Am. J. Hum. Genet. 74: 348-356, 2004. 3. Misbahuddin, A., Placzek, M. R., Chaudhuri, K. R., Wood, N. W., Bhatia, K. P., Warner, T. T. A polymorphism in the dopamine receptor DRD5 is associated with blepharospasm. Neurology 58: 124-126, 2002. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- DRD5 (Dopamine Receptor D5 (DRD5))
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别名
- DRD5
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背景
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Synonyms: D (1B) dopamine receptor,D (5) dopamine receptor,Dopamine D5 receptor,Drd5,
Tissue Specificity: Brain, liver, placenta, lymphocytes and erythrocytes.
Background: D (1B) dopamine receptor (DRD5), also called DRD1B or DRD1L2 is a protein that in humans is encoded by the DRD5 gene. This gene is mapped to 4p16.1. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. Compared with DRD1, DRD5 displayed a higher affinity for dopamine and was able to stimulate a biphasic rather than a monophasic intracellular accumulation of cAMP.
Sequence Similarities: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family.
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分子量
- 53 kDa
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途径
- Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity
抗原
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