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PROX1 抗体 (Middle Region)

Name: PROX1 抗体 (Middle Region)
SKU: ABIN3042819
Availability: OutOfStock

This anti-PROX1 antibody is a 兔多克隆 antibody detecting PROX1 in WB. Suitable for 人, 小鼠和大鼠. This Primary Antibody has been cited in 1 publication.

Anti-PROX1 antibody, Western blotting Lane 1: Rat Thymus Tissue Lysate Lane 2: HELA Cell Lysate Lane 3: JURKAT Cell Lysate Lane 4: MM231 Cell Lysate (PROX1 抗体 (Middle Region))

1 image

(1 reference)

产品编号 ABIN3042819

发货至: 中国

Quick Overview for PROX1 抗体 (Middle Region) (ABIN3042819)

抗原

See all PROX1 抗体

PROX1 (Prospero Homeobox 1 (PROX1))

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This PROX1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product PROX1 Primary Antibody

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AA 346-359, Middle Region

原理

Anti-Prospero homeobox protein 1 PROX1 Antibody Picoband®

序列

KHLAETLKQE LNTA

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Prospero homeobox protein 1 PROX1 Antibody (ABIN3042819). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence in the middle region of human PROX1, identical to the related mouse and rat sequences.

亚型

IgG
anti-Prospero Homeobox 1 (PROX1) (AA 638-737) antibody
PROX1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1H6 unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 492-522) antibody
PROX1 适用: 人, 大鼠 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 492-520) antibody
PROX1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 185-214) antibody
PROX1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 638-737) antibody
PROX1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1E7 unconjugated

anti-Prospero Homeobox 1 (PROX1) (Center) antibody
PROX1 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 444-478) antibody
PROX1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB51404 unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 1-300) antibody
PROX1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) (AA 547-737) antibody
PROX1 适用: 人, 马, Avian WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Prospero Homeobox 1 (PROX1) antibody
PROX1 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Dyer, M. A., Livesey, F. J., Cepko, C. L., Oliver, G. Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nature Genet. 34: 53-58, 2003. 2. Harvey, N. L., Srinivasan, R. S., Dillard, M. E., Johnson, N. C., Witte, M. H., Boyd, K., Sleeman, M. W., Oliver, G. Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Nature Genet. 37: 1072-1081, 2005. 3. Kazenwadel, J., Michael, M. Z., Harvey, N. L. Prox1 expression is negatively regulated by miR-181 in endothelial cells. Blood 116: 2395-2401, 2010.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

储存液

Thimerosal (Merthiolate), Sodium azide

注意事项

This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

有效期

12 months
Yang, Gao, Ma, Teng, Liu, Wei, Lu, Cheng, Hou, Zou: "Fucoidan inhibits lymphangiogenesis by downregulating the expression of VEGFR3 and PROX1 in human lymphatic endothelial cells." in: Oncotarget, Vol. 7, Issue 25, pp. 38025-38035, (2018) (PubMed).
抗原

PROX1 (Prospero Homeobox 1 (PROX1))

别名

PROX1

背景

Synonyms: Prospero homeobox protein 1,Homeobox prospero-like protein PROX1,PROX-1,PROX1,
Tissue Specificity: Most actively expressed in the developing lens. Detected also in embryonic brain, lung, liver and kidney. In adult, it is more abundant in heart and liver than in brain, skeletal muscle, kidney and pancreas. .
Background: Prospero homeobox protein 1, also called PROX1 is a protein that in humans is encoded by the PROX1 gene. This gene is mapped to 1q32.3. The protein encoded by this gene is a member of the homeobox transcription factor family. Members of this family contain a homeobox domain that consists of a 60-amino acid helix-turn-helix structure that binds DNA and RNA. The protein encoded by this gene is conserved across vertebrates and may play an essential role during development. Altered levels of this protein have been reported in cancers of different organs, such as colon, brain, blood, breast, pancreas, liver and esophagus.
Sequence Similarities: Belongs to the Prospero homeobox family.

分子量

55 kDa

UniProt

Q92786

途径

Stem Cell Maintenance, Regulation of Muscle Cell Differentiation