FGF2 抗体 (AA 143-288)
Quick Overview for FGF2 抗体 (AA 143-288) (ABIN3042812)
抗原
See all FGF2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 143-288
-
原理
- Anti-Fibroblast growth factor 2 FGF2 Antibody Picoband®
-
交叉反应 (详细)
- No cross-reactivity with other proteins
-
产品特性
- Anti-Fibroblast growth factor 2 FGF2 Antibody (ABIN3042812). Tested in ELISA, Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human FGF2 recombinant protein (Position: P143-S288).
-
亚型
- IgG
-
-
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
ELISA, 0.1-0.5 μg/mL, -
1. Doniach, T. : Basic FGF as an inducer of anteroposterior neural pattern. Cell 83: 1067-1070, 1995. 2. Eckenstein, F. P. : Fibroblast growth factors in the nervous system. J. Neurobiol. 25: 1467-1480, 1994. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
-
: "Effect of CPU-XT-008, a combretastatin A-4 analogue, on the proliferation, apoptosis and expression of vascular endothelial growth factor and basic fibroblast growth factor in human umbilical vein ..." in: Oncology letters, Vol. 11, Issue 1, pp. 491-499, (2016) (PubMed).
: "The fibroblast growth factor-2 arrests Mycobacterium avium sp. paratuberculosis growth and immunomodulates host response in macrophages." in: Tuberculosis (Edinburgh, Scotland), Vol. 95, Issue 4, pp. 505-14, (2015) (PubMed).
: "Effect of vacuum-assisted closure combined with open bone grafting to promote rabbit bone graft vascularization." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 21, pp. 1200-6, (2015) (PubMed).
: "Astragalosides promote angiogenesis via vascular endothelial growth factor and basic fibroblast growth factor in a rat model of myocardial infarction." in: Molecular medicine reports, Vol. 12, Issue 5, pp. 6718-26, (2015) (PubMed).
: "Advanced glycation end-products stimulate basic fibroblast growth factor expression in cultured Müller cells." in: Molecular medicine reports, Vol. 7, Issue 1, pp. 16-20, (2014) (PubMed).
: "MicroRNA-503 targets FGF2 and VEGFA and inhibits tumor angiogenesis and growth." in: Cancer letters, Vol. 333, Issue 2, pp. 159-69, (2013) (PubMed).
-
: "Effect of CPU-XT-008, a combretastatin A-4 analogue, on the proliferation, apoptosis and expression of vascular endothelial growth factor and basic fibroblast growth factor in human umbilical vein ..." in: Oncology letters, Vol. 11, Issue 1, pp. 491-499, (2016) (PubMed).
-
- FGF2 (Fibroblast Growth Factor 2 (Basic) (FGF2))
-
别名
- FGF2
-
背景
-
Synonyms: Fibroblast growth factor 2,FGF-2,Basic fibroblast growth factor,bFGF,Heparin-binding growth factor 2,HBGF-2,FGF2,FGFB,
Tissue Specificity: Expressed in granulosa and cumulus cells. Expressed in hepatocellular carcinoma cells, but not in non- cancerous liver tissue. .
Background: FGF2 has been implicated in a multitude of physiologic and pathologic processes, including limb development, angiogenesis, wound healing, and tumor growth. Human FGF2 shares 96 % and 97 % amino acid sequence homology with mouse and rat respectively. FGF2 belongs to the fibroblast growth factor (FGF) family. Fibroblast growth factors (FGFs) exhibit widespread mitogenic and neurotrophic activities. Nine members of the family are currently known, and FGF-1 and FGF-2 are present in relatively high levels in CNS. FGF-2 is expressed by at low levels in many tissues and cell types and reaches high concentrations in brain and pituitary.
Sequence Similarities: Belongs to the heparin-binding growth factors family.
-
分子量
- 17-21 kDa
-
UniProt
- P09038
-
途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, C21-Steroid Hormone Metabolic Process, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Protein targeting to Nucleus, S100 Proteins
抗原
-