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IL-10 抗体 (AA 19-178)

Name: IL-10 抗体 (AA 19-178)
SKU: ABIN3042802
Availability: OutOfStock

IL10 适用: 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

Anti-rat IL10 antibody, Western blotting Lane 1: Recombinant Rat IL10 Protein 10ng Lane 2: Recombinant Rat IL10 Protein 5ng Lane 3: Recombinant Rat IL10 Protein 2 (IL-10 抗体 (AA 19-178))

1 image

(16 references)

产品编号 ABIN3042802

发货至: 中国

Datasheet as PDF

抗原 See all IL-10 (IL10) 抗体

IL-10 (IL10) (Interleukin 10 (IL10))
抗原表位
36

16

16

7

6

6

5

3

2

2

2

2

1

1

1

1

1
AA 19-178
适用
137

83

48

19

17

11

8

7

6

5

4

4

2

2

1

1

1

1

1
大鼠
宿主
124

62

50

4

3

1
兔
Compatible Secondaries
克隆类型
127

111

1
多克隆
标记
157

30

12

9

6

5

3

2

2

2

2

2

2

2

2

2

2

1

1

1
This IL-10 antibody is un-conjugated
应用范围
167

114

79

53

40

27

23

18

17

15

14

14

13

13

12

8

7

6

4

4

3

3

2

2

2

1

1

1

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

原理

Rabbit IgG polyclonal antibody for Interleukin-10(IL10) detection. Tested with WB, IHC-P, ELISA in Rat.

交叉反应（详细）

No cross reactivity with other proteins.

产品特性

Rabbit IgG polyclonal antibody for Interleukin-10(IL10) detection. Tested with WB, IHC-P, ELISA in Rat.
Gene Name: interleukin 10
Protein Name: Interleukin-10(IL-10)

纯化方法

Immunogen affinity purified.

免疫原

E. coli-derived rat IL-10 recombinant protein(Position: S19-N178).

亚型

IgG

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anti-Interleukin 10 (IL10) (AA 19-178) antibody
IL10 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 10 (IL10) (AA 19-178) antibody
IL10 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 10 (IL10) antibody
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Microarray verified IL10 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB971550 unconjugated

anti-Interleukin 10 (IL10) antibody
Microarray verified IL10 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB312926 unconjugated

anti-Interleukin 10 (IL10) antibody
IL10 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Interleukin 10 (IL10) (AA 27-53) antibody
IL10 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 10 (IL10) antibody
IL10 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Interleukin 10 (IL10) (AA 1-178) antibody
IL10 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB: Concentration: 0.1-0.5 μg/mL, Species: Rat
IHC-P: Concentration: 0.5-1 μg/mL, Species: Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Species: Rat

Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

有效期

12 months
Gao, Zhao, Liu, Yuan, Wu, Xia: "Myocardial ischemic post-conditioning protects the lung against myocardial ischemia/reperfusion-induced damage by activating GSK-3β." in: Acta cirurgica brasileira, Vol. 32, Issue 5, pp. 376-387, (2017) (PubMed).

He, Liang, Guo, Huang, Niu, Dong, Wang, Zhang: "Re-polarizing Myeloid-derived Suppressor Cells (MDSCs) with Cationic Polymers for Cancer Immunotherapy." in: Scientific reports, Vol. 6, pp. 24506, (2017) (PubMed).

Li, Wu, Hang, Zhang, Li: "Women with recurrent spontaneous abortion have decreased 25(OH) vitamin D and VDR at the fetal-maternal interface." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, Vol. 50, Issue 11, pp. e6527, (2017) (PubMed).

Zhao, Gao, Liu, Jiang, Liu, Yuan, Hou, Xia: "The role of glycogen synthase kinase 3 beta in brain injury induced by myocardial ischemia/reperfusion injury in a rat model of diabetes mellitus." in: Neural regeneration research, Vol. 12, Issue 10, pp. 1632-1639, (2017) (PubMed).

Tian, Li, Li, Feng, Li, Mao, Xie, Liu, Dong, Zheng, Wang: "Bufei Yishen Granules Combined with Acupoint Sticking Therapy Suppress Inflammation in Chronic Obstructive Pulmonary Disease Rats: Via JNK/p38 Signaling Pathway." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2017, pp. 1768243, (2017) (PubMed).

Dong, Yin, Qi, Xu, Peng: "Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats." in: Nutrients, Vol. 7, Issue 6, pp. 4829-50, (2016) (PubMed).

Li, Tan, Tong, Han, Zhang, Liu, Sun: "Pentoxifylline inhibits pulmonary inflammation induced by infrarenal aorticcross-clamping dependent of adenosine receptor A2A." in: American journal of translational research, Vol. 8, Issue 5, pp. 2210-21, (2016) (PubMed).

Presti, DOrazio, Labra, La Ferla, Mezzasalma, Bizzaro, Giardina, Michelotti, Tursi, Vassallo, Di Gennaro: "Evaluation of the probiotic properties of new Lactobacillus and Bifidobacterium strains and their in vitro effect." in: Applied microbiology and biotechnology, Vol. 99, Issue 13, pp. 5613-26, (2015) (PubMed).

Shao, Li, Wang, Zhao: "IL-10 and IL-1? mediate neuropathic-pain like behavior in the ventrolateral orbital cortex." in: Neurochemical research, Vol. 40, Issue 4, pp. 733-9, (2015) (PubMed).

Gong, Wang, Yuan, Li, Gu, Zhao, Zhang, Jia, Feng, Liu: "Inhibition of Tumor Growth and Immunomodulatory Effects of Flavonoids and Scutebarbatines of Scutellaria barbata D. Don in Lewis-Bearing C57BL/6 Mice." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 630760, (2015) (PubMed).

Wang, Zhou, Chen, Zhu: "Putative role of ischemic postconditioning in a rat model of limb ischemia and reperfusion: involvement of hypoxia-inducible factor-1? expression." in: Brazilian journal of medical and biological research = Revista brasileira de pesquisas me?dicas e biolo?gicas / Sociedade Brasileira de Biofi?sica ... [et al.], Vol. 47, Issue 9, pp. 738-45, (2014) (PubMed).

Wang, Deng, Ren, Xiao, Liu, Tao: "Exogenous interleukin-10 alleviates allergic inflammation but inhibits local interleukin-10 expression in a mouse allergic rhinitis model." in: BMC immunology, Vol. 15, pp. 9, (2014) (PubMed).

Jin, Yang, Song, Zhang, Li: "Protective roles of quercetin in acute myocardial ischemia and reperfusion injury in rats." in: Molecular biology reports, Vol. 39, Issue 12, pp. 11005-9, (2012) (PubMed).

Wang, Zeng, Han, Fan, Wang: "Interleukin-10 of red nucleus plays anti-allodynia effect in neuropathic pain rats with spared nerve injury." in: Neurochemical research, Vol. 37, Issue 8, pp. 1811-9, (2012) (PubMed).

Zhang, Leng, Xue, Zhang, Wang, Kang: "Effects of penehyclidine hydrochloride in small intestinal damage caused by limb ischemia-reperfusion." in: World journal of gastroenterology, Vol. 17, Issue 2, pp. 254-9, (2011) (PubMed).

Wang, Lu, Zhang, Chen, Luo, Qin, Chen: "Increased IL-10 mRNA expression in tumor-associated macrophage correlated with late stage of lung cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 30, pp. 62, (2011) (PubMed).
抗原

IL-10 (IL10) (Interleukin 10 (IL10))

别名

IL10 (IL10 产品)

别名

CSIF antibody, GVHDS antibody, IL-10 antibody, IL10A antibody, TGIF antibody, Il-10 antibody, IL10X antibody, interleukin 10 antibody, IL10 antibody, Il10 antibody

背景

Interleukin-10(IL-10 or IL10), also known as human cytokine synthesis inhibitory factor(CSIF), is an anti-inflammatory cytokine. In humans IL-10 is encoded by the IL10 gene. It is capable of inhibiting synthesis of pro-inflammatory cytokines like IFN-gamma, IL-2, IL-3, TNFalpha and GM-CSF made by cells such as macrophages and regulatory T-cells.IL-10 also displays potent abilities to suppress the antigen presentation capacity of antigen presenting cells. Kim et al.(1992) showed that the mouse IL 10 gene contains 5 exons and spans about 5.2 kb of genomic DNA. Eskdale et al.(1997) mapped the IL10 gene to the junction between 1q31 and 1q32.

Synonyms: CSIF antibody|Cytokine Synthesis Inhibitory Factor antibody|GVHDS antibody|IL 10 antibody|IL-10 antibody|IL10 antibody|IL10A antibody|Interleukin 10 antibody|Interleukin-10 antibody|Interleukin10 antibody|MGC126450 antibody|MGC126451 antibody|T-cell growth inhibitory factor antibody|TGIF antibody

UniProt

P29456

途径

Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Maintenance of Protein Location, Cancer Immune Checkpoints