Interleukin 17a 抗体 (AA 26-158)
(2 references)Quick Overview for Interleukin 17a 抗体 (AA 26-158) (ABIN3042799)
抗原
See all Interleukin 17a (IL17A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 26-158
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原理
- Anti-IL17/IL17A Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-IL17/IL17A Antibody (ABIN3042799). Tested in ELISA, WB applications. This antibody reacts with Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse IL-17 recombinant protein (Position: A26-A158).
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亚型
- IgG
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anti-Interleukin 17A (IL17A) (AA 1-75) antibody
IL17A 适用: 人 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 4K5F6 unconjugated
anti-Interleukin 17A (IL17A) (Internal Region) antibodyIL17A 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 人 ELISA, WB, Neut 宿主: 山羊 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 17A (IL17A) (AA 24-133) antibodyIL17A 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 3G5 unconjugated
anti-Interleukin 17A (IL17A) antibodyIL17A 适用: 人 ELISA, FACS, ICC, IP 宿主: 小鼠 Monoclonal 9F9 unconjugated
anti-Interleukin 17A (IL17A) antibody (FITC)IL17A 适用: 人 ICFC 宿主: 小鼠 Monoclonal 9F9 FITC
anti-Interleukin 17A (IL17A) antibody (APC)IL17A 适用: 人 ICFC 宿主: 小鼠 Monoclonal 9F9 APC
anti-Interleukin 17A (IL17A) antibody (PE)IL17A 适用: 人 FACS 宿主: 小鼠 Monoclonal 9F9 PE
anti-Interleukin 17A (IL17A) (AA 24-155) antibodyIL17A 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA, 0.1-0.5 μg/mL, -
Western blot, 0.1-0.5 μg/mL, Mouse
1. Harrington, L. E., Hatton, R. D., Mangan, P. R., Turner, H., Murphy, T. L., Murphy, K. M., Weaver, C. T.Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages.Nature Immun. 6: 1123-1132, 2005. 2. Kennedy, J., Rossi, D. L., Zurawski, S. M., Vega, F., Jr.Kastelein, R. A., Wagner, J. L., Hannum, C. H., Zlotnick, A.: Mouse IL-17: a cytokine preferentially expressed by alpha beta TCR + CD4-CD8-T cells.J. Interferon Cytokine Res. 16: 611-617, 1996. 3. Kotake, S., Udagawa, N., Takahashi, N., Matsuzaki, K., Itoh, K., Ishiyama, S., Saito, S., Inoue, K., Kamatani, N., Gillespie, M. T., Martin, T. J., Suda, T.IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis.J. Clin. Invest. 103: 1345-1352, 1999. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide. Carrier free (No BSA)
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储存液
- Sodium azide, Without preservative
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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: "Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage." in: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 5324-9, (2015) (PubMed).
: "Th17 cells are associated with the Th1/Th2?cell balance during Echinococcus multilocularis infection." in: Molecular medicine reports, Vol. 10, Issue 1, pp. 236-40, (2014) (PubMed).
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: "Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage." in: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 5324-9, (2015) (PubMed).
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- Interleukin 17a (IL17A) (Interleukin 17A (IL17A))
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别名
- IL17A
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背景
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Synonyms: Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,Il17a,Ctla8, Il17,
Tissue Specificity: Restricted to a subset of activated T-cells. .
Background: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.
Sequence Similarities: Belongs to the immunoglobulin superfamily. CEA family.
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分子量
- 30 kDa
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UniProt
- Q62386
抗原
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