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Interleukin 17a 抗体 (AA 26-158)

Cited in 2+ publications. This anti-Interleukin 17a antibody is a 兔 多克隆 antibody detecting Interleukin 17a in ELISA 和 WB. Suitable for 小鼠.
产品编号 ABIN3042799
发货至: 中国
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Quick Overview for Interleukin 17a 抗体 (AA 26-158) (ABIN3042799)

抗原

See all Interleukin 17a (IL17A) 抗体
Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

适用

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小鼠

宿主

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克隆类型

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  • 1
多克隆

标记

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This Interleukin 17a antibody is un-conjugated

应用范围

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ELISA, Western Blotting (WB)
  • 抗原表位

    • 7
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    AA 26-158

    原理

    Anti-IL17/IL17A Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-IL17/IL17A Antibody (ABIN3042799). Tested in ELISA, WB applications. This antibody reacts with Mouse. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse IL-17 recombinant protein (Position: A26-A158).

    亚型

    IgG
  • 应用备注

    ELISA, 0.1-0.5 μg/mL, -
    Western blot, 0.1-0.5 μg/mL, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide. Carrier free (No BSA) form available in stock. If you want this antibody carrier free please specify Carrier Free or No BSA in your order note.

    储存液

    Sodium azide, Without preservative

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Li, Pan, Qiu: "Imbalances of Th17 and Treg cells and their respective cytokines in COPD patients by disease stage." in: International journal of clinical and experimental medicine, Vol. 7, Issue 12, pp. 5324-9, (2015) (PubMed).

    Ma, Wang, Zhao, Pang, Zhang, Jiang, Liu, Mamuti, Wen, Ding: "Th17 cells are associated with the Th1/Th2?cell balance during Echinococcus multilocularis infection." in: Molecular medicine reports, Vol. 10, Issue 1, pp. 236-40, (2014) (PubMed).

  • 抗原

    Interleukin 17a (IL17A) (Interleukin 17A (IL17A))

    别名

    IL17A

    背景

    Synonyms: Interleukin-17A,IL-17,IL-17A,Cytotoxic T-lymphocyte-associated antigen 8,CTLA-8,Il17a,Ctla8, Il17,

    Tissue Specificity: Restricted to a subset of activated T-cells. .

    Background: Interleukin-17A is a protein that in humans is encoded by the IL17A gene. The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis.

    Sequence Similarities: Belongs to the immunoglobulin superfamily. CEA family.

    分子量

    30 kDa

    UniProt

    Q62386
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