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CYLD 抗体 (AA 618-956)

This anti-CYLD antibody is a 兔多克隆 antibody detecting CYLD in WB. Suitable for 人和大鼠.

Anti- CYLD Picoband antibody, Western blottingAll lanes: Anti CYLD at 0. (CYLD 抗体 (AA 618-956))

1 image

产品编号 ABIN3042782

发货至: 中国

Quick Overview for CYLD 抗体 (AA 618-956) (ABIN3042782)

抗原

See all CYLD 抗体

CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

适用

44
22
16
1
1
1
1
1
1
1
1

人, 大鼠

宿主

兔

克隆类型

多克隆

标记

21
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1

This CYLD antibody is un-conjugated

应用范围

30
14
9
5
5
5
4
4
1
1
1
1

Western Blotting (WB)

Discover our top product CYLD Primary Antibody

抗原表位
15

7

5

3

2

1

1

1

1

1

1

1

1
AA 618-956

原理

Anti-CYLD Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-CYLD Antibody Picoband® (ABIN3042782). Tested in WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.

亚型

IgG
anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 170-338) antibody
CYLD 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 654-953) antibody
CYLD 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (C-Term) antibody
CYLD 适用: 人, 小鼠 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 204-358) antibody
CYLD 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 5F7F4 unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (pSer418) antibody
CYLD 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 269-435), (C-Term) antibody
CYLD 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 32-45) antibody
CYLD 适用: 人, 小鼠, Hamster, 小鸡, Cow, 犬, 豚鼠, 马, 猴, 兔 WB, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 305-582) antibody
CYLD 适用: 人 WB, FACS 宿主: 小鼠 Monoclonal 1667CT857-3-6-1 unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (AA 854-953) antibody
CYLD 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2C3 unconjugated

anti-Cylindromatosis (Turban Tumor Syndrome) (CYLD) (Internal Region) antibody
Verified CYLD 适用: 小鼠, 大鼠 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Hayashi M, Jono H, Shinriki S, Nakamura T, Guo J, Sueta A, Tomiguchi M, Fujiwara S, Yamamoto-Ibusuki M, Murakami K, Yamashita S, Yamamoto Y, Li JD, Iwase H, Ando Y. ""Clinical significance of CYLD downregulation in breast cancer"". Breast Cancer Res Treat, 2014 Feb. 2. Vanecek T, Halbhuber Z, Kacerovska D, Martinek P, Sedivcova M, Carr RA, Slouka D, Michal M, Kazakov DV. ""Large germline deletions of the CYLD gene in patients with Brooke-Spiegler syndrome and multiple familial trichoepithelioma"". Am J Dermatopathol, 2014 Nov.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

别名

CYLD

背景

Synonyms: Ubiquitin carboxyl-terminal hydrolase CYLD,3.4.19.12,Deubiquitinating enzyme CYLD,Ubiquitin thioesterase CYLD,Ubiquitin-specific-processing protease CYLD,CYLD,CYLD1, KIAA0849,HSPC057,
Tissue Specificity: Detected in fetal brain, testis, and skeletal muscle, and at a lower level in adult brain, leukocytes, liver, heart, kidney, spleen, ovary and lung. Isoform 2 is found in all tissues except kidney. .
Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Sequence Similarities: Belongs to the peptidase C19 family.

分子量

107 kDa

基因ID

1540

途径

Apoptosis, Activation of Innate immune Response

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