CYLD 抗体 (AA 618-956)
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北京 101111
Quick Overview for CYLD 抗体 (AA 618-956) (ABIN3042782)
抗原
See all CYLD 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 618-956
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原理
- Anti-CYLD Antibody
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-CYLD Antibody (ABIN3042782). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.
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亚型
- IgG
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))
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别名
- CYLD
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背景
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Synonyms: Ubiquitin carboxyl-terminal hydrolase CYLD,3.4.19.12,Deubiquitinating enzyme CYLD,Ubiquitin thioesterase CYLD,Ubiquitin-specific-processing protease CYLD,CYLD,CYLD1, KIAA0849,HSPC057,
Tissue Specificity: Detected in fetal brain, testis, and skeletal muscle, and at a lower level in adult brain, leukocytes, liver, heart, kidney, spleen, ovary and lung. Isoform 2 is found in all tissues except kidney. .
Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Sequence Similarities: Belongs to the peptidase C19 family.
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分子量
- 107 kDa
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基因ID
- 1540
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途径
- Apoptosis, Activation of Innate immune Response
抗原
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