我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Cathepsin B 抗体 (AA 80-333)

Name: Cathepsin B 抗体 (AA 80-333)
SKU: ABIN3042773
Availability: OutOfStock

There are 3+ publications for this product available. The 兔多克隆 anti-Cathepsin B antibody is suitable to detect Cathepsin B in samples from 人. It has been validated for WB.

Anti-Cathepsin B Picoband antibody, All lanes: Anti-Cathepsin B at 0. (Cathepsin B 抗体 (AA 80-333))

1 image

(3 references)

产品编号 ABIN3042773

发货至: 中国

Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111

No. 88 KeChuang 6th Street

Beijing Economic Technological Development Area

Room 801-803

4A Biotech Co.,Ltd.

Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Cathepsin B 抗体 (AA 80-333) (ABIN3042773)

抗原

See all Cathepsin B (CTSB) 抗体

Cathepsin B (CTSB)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Cathepsin B antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product CTSB Primary Antibody

抗原表位
16

6

6

4

3

2

2

1

1

1

1

1

1

1
AA 80-333

原理

Anti-Cathepsin B/CTSB Antibody

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Cathepsin B/CTSB Antibody (ABIN3042773). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Cathepsin B recombinant protein (Position: L80-D333). Human Cathepsin B shares 83% and 84% amino acid (aa) sequences identity with mouse and rat Cathepsin B, respectively.

亚型

IgG
anti-Cathepsin B (CTSB) (AA 1-339) antibody
CTSB 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin B (CTSB) (AA 251-339) antibody
CTSB 适用: 人, 大鼠, 小鼠 WB, ELISA, ICC, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin B (CTSB) (AA 82-333) antibody
CTSB 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin B (CTSB) antibody
CTSB 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-Cathepsin B (CTSB) antibody
KD Validated CTSB 适用: 人 WB 宿主: 兔 Monoclonal 23GB1130 unconjugated Recombinant Antibody

anti-Cathepsin B (CTSB) (AA 1-339) antibody
CTSB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Cathepsin B (CTSB) (AA 129-333) antibody
CTSB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin B (CTSB) (AA 129-333) antibody
CTSB 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin B (CTSB) (AA 129-333) antibody
CTSB 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cathepsin B (CTSB) (AA 251-339) antibody (AbBy Fluor® 680)
CTSB 适用: 人, 大鼠, 小鼠 WB, FACS, IF (cc), IF (p) 宿主: 兔 Polyclonal AbBy Fluor® 680

应用备注

Western blot, 0.1-0.5 μg/mL, Human

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Zheng, Li, Wang, Wang, Liao, Hu, Fan, Kang, Zeng, Wu, Wu, Zhang, Wang, He et al.: "Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage ..." in: Autophagy, Vol. 12, Issue 9, pp. 1593-613, (2017) (PubMed).

Zhang, Mai, Yang, Dong, Zheng, Yang: "CTSB promotes porcine preadipocytes differentiation by degrading fibronectin and attenuating the Wnt/β-catenin signaling pathway." in: Molecular and cellular biochemistry, Vol. 395, Issue 1-2, pp. 53-64, (2014) (PubMed).

Yang, Lü, Hong, Xi, Zhang: "The molecular mechanism for effects of TiN coating on NiTi alloy on endothelial cell function." in: Biomaterials, Vol. 35, Issue 24, pp. 6195-205, (2014) (PubMed).
抗原

Cathepsin B (CTSB)

别名

CTSB

背景

Synonyms: Cathepsin B,3.4.22.1,APP secretase,APPS,Cathepsin B1,Cathepsin B light chain,Cathepsin B heavy chain,CTSB,CPSB,
Tissue Specificity: Expressed in all cell types so far analyzed.
Background: < a href="https://www.bosterbio.com/anti-cathepsin-b-picoband-trade-antibody-pb9046-boster.html" style="color:#ea8d28">Cathepsin B is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSB gene. And this gene is mapped to chromosome 8p22. The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is a member of the peptidase C1 family. Cathepsin B was once suspected as a candidate protease participating in the conversion of beta-amyloid precursor protein into the amyloid plaques found in Alzheimer's disease patients. However, this function is now known to be mediated by BACE1 protease. It is now thought that cathepsin B can degrade beta-amyloid precursor protein into harmless fragments. Thus, it is conceivable cathepsin B may play a pivotal role in the natural defense against Alzheimer's disease. Overexpression of cathepsin B has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene. The standard product used in this kit is recombinant human Cathepsin B with the molecular mass of 37KDa.
Sequence Similarities: Belongs to the peptidase C1 family.

分子量

33 kDa

基因ID

1508

UniProt

P07858

途径

Activation of Innate immune Response, Toll-Like Receptors Cascades