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CSK 抗体 (AA 2-204)

Name: CSK 抗体 (AA 2-204)
SKU: ABIN3042764
Availability: OutOfStock

CSK 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

Anti-CSK Picoband antibody, All lanes: Anti CSK at 0. (CSK 抗体 (AA 2-204))

Western Blotting (WB) image for anti-C-Src tyrosine Kinase (CSK) (AA 2-204) antibody (ABIN3042764) (CSK 抗体 (AA 2-204))

3 images

产品编号 ABIN3042764

发货至: 中国

Datasheet as PDF

抗原 See all CSK 抗体

CSK (C-Src tyrosine Kinase (CSK))
抗原表位
16

15

8

8

7

6

6

4

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 2-204
适用
95

51

41

3

3

2

1

1

1

1
人, 小鼠, 大鼠
宿主
86

9

2
兔
Compatible Secondaries
克隆类型
83

13
多克隆
标记
48

7

6

5

3

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1
This CSK antibody is un-conjugated
应用范围
86

36

24

24

15

14

13

8

7

6

5

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC)

原理

Anti-Csk Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Csk Antibody Picoband® (ABIN3042764). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human CSK recombinant protein (Position: S2-G204). Human CSK shares 99% amino acid (aa) sequence identity with both mouse and rat CSK.

亚型

IgG

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CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated

anti-C-Src tyrosine Kinase (CSK) antibody
CSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) antibody
CSK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5F3 unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 243-438) antibody
CSK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 325-416) antibody
CSK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 67-101), (N-Term) antibody
CSK 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50568 unconjugated

anti-C-Src tyrosine Kinase (CSK) (Ser280) antibody
CSK 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 1-200) antibody
CSK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibody
CSK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-C-Src tyrosine Kinase (CSK) (pSer364) antibody
CSK 适用: 人, 大鼠 WB, ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

应用备注

Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. Bergman M, Mustelin T, Oetken C, Partanen J, Flint NA, Amrein KE, Autero M, Burn P, Alitalo K (August 1992). "The human p50csk tyrosine kinase phosphorylates p56lck at Tyr-505 and down regulates its catalytic activity. 2. Sun G, Budde RJ (September 1997). "Expression, purification, and initial characterization of human Yes protein tyrosine kinase from a bacterial expression system". Arch. Biochem. Biophys. 345 (1): 135-42. 3. Nada S, Okada M, MacAuley A, Cooper JA, Nakagawa H (May 1991). "Cloning of a complementary DNA for a protein-tyrosine kinase that specifically phosphorylates a negative regulatory site of p60c-src". Nature 351 (6321): 69-72.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

CSK (C-Src tyrosine Kinase (CSK))

别名

CSK (CSK 产品)

背景

Synonyms: Tyrosine-protein kinase CSK,2.7.10.2,C-Src kinase,Protein-tyrosine kinase CYL,CSK,
Tissue Specificity: Expressed in lung and macrophages. .
Background: CSK also known as C-Src kinase, is a non-receptor protein tyrosine kinase protein that in humans is encoded by the CSK gene. It is mapped to 15q24.1. CSK suppresses activity of the Src family of protein kinases by phosphorylation of Src family members at a conserved C-terminal site in Src. Csk's control of the Src family activity is widely thought to be central to regulation of the immune response. CSK can downregulate tyrosine kinase activity of the SRC oncoprotein through tyrosine phosphorylation of the SRC carboxy terminus. Since cell transformation by SRC oncoproteins is caused by various mechanisms that interfere with this phosphorylation, the CSK gene might function as an antioncogene.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.

分子量

51 kDa

基因ID

1445

UniProt

P41240

途径

TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events