CSK 抗体 (AA 2-204)
Quick Overview for CSK 抗体 (AA 2-204) (ABIN3042764)
抗原
See all CSK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-204
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原理
- Anti-Csk Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Csk Antibody (ABIN3042764). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human CSK recombinant protein (Position: S2-G204). Human CSK shares 99% amino acid (aa) sequence identity with both mouse and rat CSK.
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亚型
- IgG
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anti-C-Src tyrosine Kinase (CSK) (AA 1-100) antibody
CSK 适用: 人 WB, ELISA, IP, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyCSK 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (C-Term) antibodyVerified CSK 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) antibodyCSK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, ICC, FACS 宿主: 小鼠 Monoclonal 5F3 unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 243-438) antibodyCSK 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 1-200) antibodyCSK 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 241-450) antibodyCSK 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 325-416) antibodyCSK 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 67-101), (N-Term) antibodyCSK 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB50568 unconjugated
anti-C-Src tyrosine Kinase (CSK) (AA 1-450) antibodyCSK 适用: 人 WB, ELISA, IF, ICC 宿主: 小鼠 Monoclonal AT7C6 unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- CSK (C-Src tyrosine Kinase (CSK))
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别名
- CSK
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背景
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Synonyms: Tyrosine-protein kinase CSK,2.7.10.2,C-Src kinase,Protein-tyrosine kinase CYL,CSK,
Tissue Specificity: Expressed in lung and macrophages. .
Background: CSK also known as C-Src kinase, is a non-receptor protein tyrosine kinase protein that in humans is encoded by the CSK gene. It is mapped to 15q24.1. CSK suppresses activity of the Src family of protein kinases by phosphorylation of Src family members at a conserved C-terminal site in Src. Csk's control of the Src family activity is widely thought to be central to regulation of the immune response. CSK can downregulate tyrosine kinase activity of the SRC oncoprotein through tyrosine phosphorylation of the SRC carboxy terminus. Since cell transformation by SRC oncoproteins is caused by various mechanisms that interfere with this phosphorylation, the CSK gene might function as an antioncogene.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. CSK subfamily.
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分子量
- 51 kDa
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基因ID
- 1445
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UniProt
- P41240
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途径
- TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
抗原
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