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M-CSF/CSF1 抗体 (AA 33-262)

CSF1 适用: 小鼠, 大鼠 ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042763
发货至: 中国
  • 抗原 See all M-CSF/CSF1 (CSF1) 抗体
    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
    抗原表位
    • 15
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    AA 33-262
    适用
    • 93
    • 49
    • 15
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    • 1
    小鼠, 大鼠
    宿主
    • 97
    • 12
    • 4
    • 2
    • 1
    克隆类型
    • 95
    • 20
    • 1
    多克隆
    标记
    • 55
    • 12
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    • 1
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    This M-CSF/CSF1 antibody is un-conjugated
    应用范围
    • 79
    • 51
    • 31
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    • 11
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    • 8
    • 6
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    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Macrophage colony-stimulating factor 1(CSF1) detection. Tested with IHC-P, ELISA in Mouse,Rat.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Macrophage colony-stimulating factor 1(CSF1) detection. Tested with IHC-P, ELISA in Mouse,Rat.
    Gene Name: colony stimulating factor 1 (macrophage)
    Protein Name: Macrophage colony-stimulating factor 1
    纯化方法
    Immunogen affinity purified.
    免疫原
    E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.
    亚型
    IgG
    Top Product
    Discover our top product CSF1 Primary Antibody
  • 应用备注
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Pei, Sun, Zhang, Wang, Ren: "Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer." in: The Journal of thoracic and cardiovascular surgery, Vol. 148, Issue 4, pp. 1208-1216.e2, (2015) (PubMed).

  • 抗原
    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
    别名
    CSF1 (CSF1 产品)
    别名
    CSF-1 antibody, MCSF antibody, C87615 antibody, Csfm antibody, op antibody, csf1-1 antibody, zgc:172186 antibody, CSF1 antibody, csf1-2 antibody, zgc:158436 antibody, colony stimulating factor 1 antibody, colony stimulating factor 1 (macrophage) antibody, colony stimulating factor 1a (macrophage) antibody, macrophage colony-stimulating factor 1 antibody, macrophage colony stimulating factor antibody, colony stimulating factor 1b (macrophage) antibody, CSF1 antibody, Csf1 antibody, csf1a antibody, LOC396599 antibody, LOC100860895 antibody, csf1b antibody
    背景
    M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

    Synonyms: Colony stimulating factor 1 (macrophage) antibody|Colony stimulating factor 1 antibody| Colony stimulating factor macrophage specific antibody|CSF 1 antibody|CSF-1 antibody|CSF1 antibody|CSF1_HUMAN antibody|Csfm antibody|Lanimostim antibody|M CSF antibody|M-CSF antibody|Macrophage Colony Stimulating Factor 1 antibody|Macrophage colony stimulating factor antibody|MCSF antibody|MGC31930 antibody|Processed macrophage colony-stimulating factor 1 antibody
    基因ID
    12977
    UniProt
    P07141
    途径
    RTK signaling
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