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M-CSF/CSF1 抗体 (AA 33-262)

This 兔 多克隆 antibody specifically detects M-CSF/CSF1 in ELISA 和 IHC. It exhibits reactivity toward 小鼠 和 大鼠.It has been mentioned in 1 publication
产品编号 ABIN3042763
发货至: 中国
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Quick Overview for M-CSF/CSF1 抗体 (AA 33-262) (ABIN3042763)

抗原

See all M-CSF/CSF1 (CSF1) 抗体
M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

适用

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小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This M-CSF/CSF1 antibody is un-conjugated

应用范围

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ELISA, Immunohistochemistry (IHC)
  • 抗原表位

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    AA 33-262

    原理

    Anti-MCSF/CSF1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-MCSF/CSF1 Antibody (ABIN3042763). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.

    亚型

    IgG
  • 应用备注

    ELISA, 0.1-0.5 μg/mL, -
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat

    说明

    Antibody can be supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Pei, Sun, Zhang, Wang, Ren: "Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer." in: The Journal of thoracic and cardiovascular surgery, Vol. 148, Issue 4, pp. 1208-1216.e2, (2015) (PubMed).

  • 抗原

    M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

    别名

    Csf1

    背景

    Synonyms: Macrophage colony-stimulating factor 1,CSF-1,MCSF,Processed macrophage colony-stimulating factor 1,Csf1,Csfm,

    Tissue Specificity: Non-neural epithelial tissues.

    Background: M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

    Sequence Similarities: Contains 5 cadherin domains.

    分子量

    130 kDa

    基因ID

    12977

    UniProt

    P07141

    途径

    RTK signaling
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