M-CSF/CSF1 抗体 (AA 33-262)
(1 reference)Quick Overview for M-CSF/CSF1 抗体 (AA 33-262) (ABIN3042763)
抗原
See all M-CSF/CSF1 (CSF1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 33-262
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原理
- Anti-MCSF/CSF1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MCSF/CSF1 Antibody Picoband® (ABIN3042763). Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.
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亚型
- IgG
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anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-204) antibody
CSF1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) antibodyCSF1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 201-300) antibodyCSF1 适用: 人, 小鼠 WB, ELISA, ICC, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (Middle Region) antibodyCSF1 适用: 人, 小鼠, 大鼠, 犬, Pig, 豚鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-132) antibodyCSF1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 261-427) antibodyCSF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 230-257) antibodyCSF1 适用: 人 WB, IF, FACS, IHC (p) 宿主: 兔 Polyclonal RB18764 unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (C-Term) antibodyCSF1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) (AA 33-554) antibodyCSF1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Colony Stimulating Factor 1 (Macrophage) (CSF1) antibody (Biotin)CSF1 适用: 人 WB, ELISA, Neut 宿主: 兔 Polyclonal Biotin
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应用备注
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ELISA, 0.1-0.5 μg/mL, -
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat
1. Fixe P, Praloran V (June 1997)."Macrophage colony-stimulating-factor (M-CSF or CSF-1) and its receptor: structure-function relationships". Eur. Cytokine Netw. 8 (2): 125-36. 2. Nemunaitis J (April 1993). "Macrophage function activating cytokines: potential clinical application". Crit. Rev. Oncol. Hematol. 14 (2): 153-71. 3. Stanley ER, Berg KL, Einstein DB, Lee PS, Pixley FJ, Wang Y, Yeung YG (January 1997). "Biology and action of colony--stimulating factor-1". Mol. Reprod. Dev. 46(1): 4-10. -
说明
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Antibody can be supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer." in: The Journal of thoracic and cardiovascular surgery, Vol. 148, Issue 4, pp. 1208-1216.e2, (2015) (PubMed).
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: "Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer." in: The Journal of thoracic and cardiovascular surgery, Vol. 148, Issue 4, pp. 1208-1216.e2, (2015) (PubMed).
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- M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))
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别名
- Csf1
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背景
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Synonyms: Macrophage colony-stimulating factor 1,CSF-1,MCSF,Processed macrophage colony-stimulating factor 1,Csf1,Csfm,
Tissue Specificity: Non-neural epithelial tissues.
Background: M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
Sequence Similarities: Contains 5 cadherin domains.
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分子量
- 130 kDa
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基因ID
- 12977
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UniProt
- P07141
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途径
- RTK signaling
抗原
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