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Claudin 2 抗体 (AA 38-230)

This 兔 多克隆 antibody specifically detects Claudin 2 in WB 和 IHC. It exhibits reactivity toward 人 和 大鼠.It has been mentioned in 1 publication
产品编号 ABIN3042751
发货至: 中国
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Quick Overview for Claudin 2 抗体 (AA 38-230) (ABIN3042751)

抗原

See all Claudin 2 (CLDN2) 抗体
Claudin 2 (CLDN2)

适用

  • 84
  • 22
  • 16
  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
人, 大鼠

宿主

  • 82
  • 5

克隆类型

  • 80
  • 7
多克隆

标记

  • 43
  • 7
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  • 2
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  • 2
  • 2
This Claudin 2 antibody is un-conjugated

应用范围

  • 61
  • 49
  • 40
  • 23
  • 10
  • 8
  • 7
  • 6
  • 2
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 16
    • 10
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    • 4
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    • 2
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    • 1
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    • 1
    AA 38-230

    原理

    Anti-Claudin 2/CLDN2 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Claudin 2/CLDN2 Antibody (ABIN3042751). Tested in IHC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human Claudin 2 recombinant protein (Position: A38-V230). Human Claudin 2 shares 92% amino acid (aa) sequence identity with mouse Claudin 2.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Rat, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Cen, Liu, Li, He, Wang, Liu, Liu, Ji: "Alteration in P-glycoprotein at the blood-brain barrier in the early period of MCAO in rats." in: The Journal of pharmacy and pharmacology, Vol. 65, Issue 5, pp. 665-72, (2013) (PubMed).

  • 抗原

    Claudin 2 (CLDN2)

    别名

    CLDN2

    背景

    Synonyms: Claudin-2,SP82,CLDN2,PSEC0059, SP82, UNQ705/PRO1356,

    Background: Claudin-2 is a protein that in humans is encoded by the CLDN2 gene. By genomic sequence analysis, this gene is mapped to chromosome Xq22.3-q23. This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. By expression in a human intestinal epithelial cell line, it was determined that the intestine-specific homeodomain proteins CDX1 and CDX2 activated a reporter plasmid driven by the CLDN2 promoter.

    分子量

    25 kDa

    基因ID

    9075

    UniProt

    P57739

    途径

    Hepatitis C
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