CDK7 抗体 (AA 31-346)
Quick Overview for CDK7 抗体 (AA 31-346) (ABIN3042742)
抗原
See all CDK7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 31-346
-
原理
- Anti-Cdk7 Antibody Picoband®
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
产品特性
- Anti-Cdk7 Antibody Picoband® (ABIN3042742). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- E.coli-derived human Cdk7 recombinant protein (Position: D31-F346). Human Cdk7 shares 94.9% and 96.1% amino acid (aa) sequence identity with mouse and rat Cdk7, respectively.
-
亚型
- IgG
-
-
anti-Cyclin-Dependent Kinase 7 (CDK7) (AA 1-346) antibody
CDK7 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (AA 1-346) antibodyCDK7 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (AA 1-346) antibodyCDK7 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibodyCDK7 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (AA 211-346) antibodyCDK7 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (pThr170) antibodyCDK7 适用: 人, 小鼠 WB, IHC (p), DB 宿主: 兔 Polyclonal RB07518 unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibodyCDK7 适用: 人, 小鼠, 大鼠, Cow, 马, Pig, 犬, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (AA 1-80) antibodyCDK7 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro), FACS 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (AA 212-341) antibodyCDK7 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibodyCDK7 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
Western blot, 0.1-0.5 μg/mL, Human
1. Chen, J., Larochelle, S., Li, X., Suter, B. Xpd/Ercc2 regulates CAK activity and mitotic progression. Nature 424: 228-232, 2003. 2. Larochelle, S., Merrick, K. A., Terret, M.-E., Wohlbold, L., Barboza, N. M., Zhang, C., Shokat, K. M., Jallepalli, P. V., Fisher, R. P. Requirements for Cdk7 in the assembly of Cdk1/cyclin B and activation of Cdk2 revealed by chemical genetics in human cells. Molec. Cell 25: 839-850, 2007. 3. Levedakou, E. N., He, M., Baptist, E. W., Craven, R. J., Cance, W. G., Welcsh, P. L., Simmons, A., Naylor, S. L., Leach, R. L., Lewis, T. B., Bowcock, A., Liu, E. T. Two novel human serine/threonine kinases with homologies to the cell cycle regulating Xenopus MO15, and NIMA kinases: cloning and characterization of their expression pattern. Oncogene 9: 1977-1988, 1994. 4. Shiekhattar, R., Mermelstein, F., Fisher, R. P., Drapkin, R., Dynlacht, B., Wessling, H. C., Morgan, D. O., Reinberg. Cdk-activating kinase complex is a component of human transcription factor TFIIH. Nature 374: 283-287, 1995. -
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
-
-
- CDK7 (Cyclin-Dependent Kinase 7 (CDK7))
-
别名
- CDK7
-
背景
-
Synonyms: Cyclin-dependent kinase 7,2.7.11.22,2.7.11.23,39 kDa protein kinase,p39 Mo15,CDK-activating kinase 1,Cell division protein kinase 7,Serine/threonine-protein kinase 1,TFIIH basal transcription factor complex kinase subunit,CDK7,CAK, CAK1, CDKN7, MO15, STK1,
Tissue Specificity: Ubiquitous.
Background: Cyclin-dependent kinase 7, also known as cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. The gene was assigned to human chromosome 5q13.2. Serine/threonine kinase involved in cell cycle control and in RNA polymerase II-mediated RNA transcription. CDK7 is the catalytic subunit of the CDK-activating kinase (CAK) complex. It is required for DNA-bound peptides-mediated transcription and cellular growth inhibition.
Sequence Similarities: Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.
-
分子量
- 39 kDa
-
基因ID
- 1022
-
UniProt
- P50613
-
途径
- Cell Division Cycle, DNA Damage Repair, Intracellular Steroid Hormone Receptor Signaling Pathway, Mitotic G1-G1/S Phases, M Phase
抗原
-
