STAT5B 抗体 (C-Term)
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Quick Overview for STAT5B 抗体 (C-Term) (ABIN3042740)
抗原
See all STAT5B 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- Anti-STAT5b Antibody
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序列
- KDEVYSKYYT PVPCESATAK AVDGYVKPQ
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特异性
- No cross reactivity with other proteins.
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交叉反应 （详细）
- No cross-reactivity with other proteins
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预测反应
- different from the related mouse,rat sequences by two amino acids.
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产品特性
- Anti-STAT5b Antibody. Tested in Flow Cytometry, IF, ICC, WB applications. This antibody reacts with Human, Mouse, Rat.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human STAT5b, different from the related mouse and rat sequences by two amino acids.
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亚型
- IgG
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anti-Signal Transducer and Activator of Transcription 5B (STAT5B) antibody
KD Validated STAT5B 适用: 人 WB, FACS, IF (p) 宿主: 兔 Monoclonal 24GB2110 unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-390) antibodySTAT5B 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1A1 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 1-390) antibodySTAT5B 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1C2 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 678-787) antibodySTAT5B 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 2D1 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 737-787) antibodySTAT5B 适用: 人, 小鼠 WB, IHC, IP, ICC, FACS 宿主: 兔 Monoclonal BLR146J unconjugated Recombinant Antibody
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) antibodySTAT5B 适用: 人 WB, IHC (p) 宿主: 兔 Monoclonal 12A1 unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 40-280) antibodySTAT5B 适用: 人 WB, IHC, ELISA, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 40-280) antibodySTAT5B 适用: 人 WB, IHC, ELISA, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (N-Term) antibodySTAT5B 适用: 人, 小鼠, 大鼠, 犬, 马, Pig, 兔, 小鸡 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Signal Transducer and Activator of Transcription 5B (STAT5B) (AA 180-229) antibodySTAT5B 适用: 人, Cow, 犬, 马, Pig, 绵羊 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
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应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Immunocytochemistry/Immunofluorescence, 2 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- STAT5B (Signal Transducer and Activator of Transcription 5B (STAT5B))
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别名
- STAT5B
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背景
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Background: STAT5B (Signal transducer and activator of transcription 5B) is a protein that in humans is encoded by the STAT5B gene. STAT5B orthologs have been identified in most placentals for which complete genome data are available. By FISH, Lin et al. (1996) mapped STAT5B to 17q11.2. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APML). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APML.
Gene Full Name: signal transducer and activator of transcription 5B
Sequence Similarities: Belongs to the transcription factor STAT family.
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分子量
- 90 kDa
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基因ID
- 6777
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UniProt
- P51692
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途径
- JAK/STAT Signaling, RTK signaling, Response to Growth Hormone Stimulus, C21-Steroid Hormone Metabolic Process, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, CXCR4-mediated Signaling Events, Activated T Cell Proliferation
抗原
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