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IL-13 抗体 (AA 22-131)

There is 1 publication for this product available. The 兔 多克隆 anti-IL-13 antibody is suitable to detect IL-13 in samples from 大鼠. It has been validated for ELISA.
产品编号 ABIN3042737
发货至: 中国
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Quick Overview for IL-13 抗体 (AA 22-131) (ABIN3042737)

抗原

See all IL-13 (IL13) 抗体
IL-13 (IL13) (Interleukin 13 (IL13))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This IL-13 antibody is un-conjugated

应用范围

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ELISA
  • 抗原表位

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    AA 22-131

    原理

    Anti-Interleukin-13 IL13 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Interleukin-13 IL13 Antibody (ABIN3042737). Tested in ELISA applications. This antibody reacts with Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E. coli-derived rat IL-13 recombinant protein (Position: P22-H131). Rat IL-13 shares 62% and 76% amino acid (aa) sequence identity with human and mouse IL-13, respectively.

    亚型

    IgG
  • 应用备注

    ELISA(Cap), 0.1-0.5 μg/mL, Rat

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Li, Li, Zuo, Ke, Yan, Wen, Zhang, Yang: "T-helper type-2 contact hypersensitivity of Balb/c mice aggravated by dibutyl phthalate via long-term dermal exposure." in: PLoS ONE, Vol. 9, Issue 2, pp. e87887, (2014) (PubMed).

  • 抗原

    IL-13 (IL13) (Interleukin 13 (IL13))

    别名

    IL13

    背景

    Synonyms: Interleukin-13,IL-13,T-cell activation protein P600,Il13,Il-13,

    Tissue Specificity: Activated T-cells, mast cells, natural killer cells.

    Background: IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

    Sequence Similarities: Belongs to the IL-4/IL-13 family.

    分子量

    37 kDa

    基因ID

    116553

    UniProt

    P42203

    途径

    JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport
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