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Serotonin Receptor 2B 抗体 (C-Term)

This anti-Serotonin Receptor 2B antibody is a 兔 多克隆 antibody detecting Serotonin Receptor 2B in WB. Suitable for 人 和 大鼠.
产品编号 ABIN3042730
发货至: 中国
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Quick Overview for Serotonin Receptor 2B 抗体 (C-Term) (ABIN3042730)

抗原

See all Serotonin Receptor 2B (HTR2B) 抗体
Serotonin Receptor 2B (HTR2B)

适用

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人, 大鼠

宿主

  • 50
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克隆类型

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多克隆

标记

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This Serotonin Receptor 2B antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 446-478, C-Term

    原理

    Anti-5HT2B Receptor/HTR2B Antibody

    序列

    MRLRSSTIQS SSIILLDTLL LTENEGDKTE EQ

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-5HT2B Receptor/HTR2B Antibody (ABIN3042730). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2B Receptor, different from the related mouse sequence by six amino acids, and from the related rat sequence by nine amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    Serotonin Receptor 2B (HTR2B)

    别名

    HTR2B

    背景

    Synonyms: 5-hydroxytryptamine receptor 2B,5-HT-2B,5-HT2B,Serotonin receptor 2B,HTR2B,

    Tissue Specificity: Ubiquitous. Detected in liver, kidney, heart, pulmonary artery, and intestine. Detected at lower levels in blood, placenta and brain, especially in cerebellum, occipital cortex and frontal cortex. .

    Background: 5HT2B Receptor is known as HTR2B. This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved.

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

    分子量

    54 kDa

    基因ID

    3357

    UniProt

    P41595

    途径

    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of Carbohydrate Metabolic Process
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