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HTR2A 抗体 (C-Term)

This 兔 多克隆 anti-HTR2A antibody specifically detects HTR2A in WB 和 IHC. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN3042729
发货至: 中国
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Quick Overview for HTR2A 抗体 (C-Term) (ABIN3042729)

抗原

See all HTR2A 抗体
HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This HTR2A antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    AA 400-431, C-Term

    原理

    Anti-5HT2A Receptor/HTR2A Antibody

    序列

    KENKKPLQLI LVNTIPALAY KSSQLQMGQK KN

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-5HT2A Receptor/HTR2A Antibody (ABIN3042729). Tested in IHC, WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human 5HT2A Receptor , different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    HTR2A (5-Hydroxytryptamine (serotonin) Receptor 2A (HTR2A))

    别名

    HTR2A

    背景

    Synonyms: 5-hydroxytryptamine receptor 2A,5-HT-2,5-HT-2A,Serotonin receptor 2A,HTR2A,HTR2,

    Tissue Specificity: Detected in brain cortex (at protein level). Detected in blood platelets. .

    Background: The mammalian HTR2A (5-HT2A receptor) is a subtype of the 5-HT2 receptor that belongs to the serotonin receptor family and is a G protein-coupled receptor (GPCR). This is the main excitatory receptor subtype among the GPCRs for serotonin (5-HT), although 5-HT2A may also have an inhibitory effect on certain areas such as the visual cortex and the orbit frontal cortex. This receptor was given importance first as the target of psychedelic drugs like LSD. Later it came back to prominence because it was also found to be mediating, at least partly, the action of many antipsychotic drugs, especially the atypical ones. 5-HT2A also happens to be a necessary receptor for the spread of the human polyoma virus called JC virus. Sparkes et al. (1991) concluded that the gene is located on 13q14-q21 in man and on chromosome 14 in the mouse.

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family.

    分子量

    53 kDa

    基因ID

    3356

    UniProt

    P28223

    途径

    JAK/STAT Signaling, Inositol Metabolic Process, Regulation of Carbohydrate Metabolic Process
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