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LHCGR 抗体 (N-Term)

Cited in 1 publication. The 兔 多克隆 anti-LHCGR antibody (ABIN3042675) specifically detects LHCGR in WB 和 IHC. The antibody is reactive with 人 和 大鼠 samples.
产品编号 ABIN3042675
发货至: 中国
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Quick Overview for LHCGR 抗体 (N-Term) (ABIN3042675)

抗原

See all LHCGR 抗体
LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

适用

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人, 大鼠

宿主

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克隆类型

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多克隆

标记

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This LHCGR antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    N-Term

    原理

    Anti-hCG receptor/LHCGR Antibody

    序列

    YLSICNTGIR KFPDVTK

    特异性

    No cross reactivity with other proteins.

    交叉反应 (详细)

    No cross-reactivity with other proteins

    预测反应

    different from the relative rat sequence by two amino acids,mouse sequence by three amino acids.

    产品特性

    Anti-hCG receptor/LHCGR Antibody. Tested in IHC, WB applications. This antibody reacts with Human, Rat.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human hCG receptor, different from the relative rat sequence by two amino acids, mouse sequence by three amino acids.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human Western blot, 0.1-0.5 μg/mL, Human, Rat

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Wu, Shi, Gong, Yu, Chen, Wang, Sun: "Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127595, (2016) (PubMed).

  • 抗原

    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))

    别名

    LHCGR

    背景

    Background: The luteinizing hormone/choriogonadotropin receptor is a member of a subfamily of G protein-coupled receptors (GPCR) characterized by the presence of a large N-terminal extracellular domain containing several leucine-rich repeats (LRR). This glycoprotein hormone receptor family has been named the LRR-containing GPCR (LGR) family. The LHCGR gene contains 11 exons and spans approximately 80 kb and it is mapped to chromosome 2p21. In the ovary, theca, stromal, late-stage (luteinizing) granulosa, and luteal cells contain LHCGR. In the testes, Leydig cells contain LHCRG.

    Gene Full Name: luteinizing hormone/choriogonadotropin receptor

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.

    分子量

    78 kDa

    基因ID

    3973

    UniProt

    P22888

    途径

    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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