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- 抗原 See all LHCGR 抗体
- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
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抗原表位
- AA 127-143, N-Term
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适用
- 人, 大鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LHCGR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-hCG receptor/LHCGR Antibody Picoband®
- 序列
- YLSICNTGIR KFPDVTK
- 交叉反应 (详细)
- No cross-reactivity with other proteins
- 产品特性
- Anti-hCG receptor/LHCGR Antibody (ABIN3042675). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human hCG receptor, different from the relative rat sequence by two amino acids, mouse sequence by three amino acids.
- 亚型
- IgG
- Top Product
- Discover our top product LHCGR Primary Antibody
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human
Western blot, 0.1-0.5 μg/mL, Human, Rat
1. Ascoli, M., Fanelli, F., Segaloff, D. L.The lutropin/choriogonadotropin receptor, a 2002 perspective.Endocr. Rev. 23: 141-174, 2002. 2. Themmen, A. P. N., Huhtaniemi, I. T.Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.Endocr. Rev. 21: 551-583, 2000. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- 储存液
- Thimerosal (Merthiolate), Sodium azide
- 注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. - 有效期
- 12 months
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Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127595, (2016) (PubMed).
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Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127595, (2016) (PubMed).
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- 抗原
- LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
- 别名
- LHCGR (LHCGR 产品)
- 背景
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Synonyms: Lutropin-choriogonadotropic hormone receptor,LH/CG-R,Luteinizing hormone receptor,LHR,LSH-R,LHCGR,LCGR, LGR2, LHRHR,
Tissue Specificity: Gonadal and thyroid cells.
Background: The luteinizing hormone/choriogonadotropin receptor is a member of a subfamily of G protein-coupled receptors (GPCR) characterized by the presence of a large N-terminal extracellular domain containing several leucine-rich repeats (LRR). This glycoprotein hormone receptor family has been named the LRR-containing GPCR (LGR) family. The LHCGR gene contains 11 exons and spans approximately 80 kb and it is mapped to chromosome 2p21. In the ovary, theca, stromal, late-stage (luteinizing) granulosa, and luteal cells contain LHCGR. In the testes, Leydig cells contain LHCRG.
Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.
- 分子量
- 78 kDa
- UniProt
- P22888
- 途径
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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