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LHCGR 抗体 (N-Term)

LHCGR 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042675
发货至: 中国
  • 抗原 See all LHCGR 抗体
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    抗原表位
    • 21
    • 14
    • 6
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 127-143, N-Term
    适用
    • 70
    • 27
    • 21
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 48
    • 27
    • 1
    克隆类型
    • 49
    • 27
    多克隆
    标记
    • 31
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This LHCGR antibody is un-conjugated
    应用范围
    • 50
    • 31
    • 28
    • 21
    • 14
    • 12
    • 12
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    原理
    Anti-hCG receptor/LHCGR Antibody Picoband®
    序列
    YLSICNTGIR KFPDVTK
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-hCG receptor/LHCGR Antibody (ABIN3042675). Tested in IHC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the N-terminus of human hCG receptor, different from the relative rat sequence by two amino acids, mouse sequence by three amino acids.
    亚型
    IgG
    Top Product
    Discover our top product LHCGR Primary Antibody
  • 应用备注
    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat, Human
    Western blot, 0.1-0.5 μg/mL, Human, Rat
    1. Ascoli, M., Fanelli, F., Segaloff, D. L.The lutropin/choriogonadotropin receptor, a 2002 perspective.Endocr. Rev. 23: 141-174, 2002. 2. Themmen, A. P. N., Huhtaniemi, I. T.Mutations of gonadotropins and gonadotropin receptors: elucidating the physiology and pathophysiology of pituitary-gonadal function.Endocr. Rev. 21: 551-583, 2000.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • Wu, Shi, Gong, Yu, Chen, Wang, Sun: "Evaluation of follicular synchronization caused by estrogen administration and its reproductive outcome." in: PLoS ONE, Vol. 10, Issue 5, pp. e0127595, (2016) (PubMed).

  • 抗原
    LHCGR (Luteinizing Hormone/Choriogonadotropin Receptor (LHCGR))
    别名
    LHCGR (LHCGR 产品)
    背景

    Synonyms: Lutropin-choriogonadotropic hormone receptor,LH/CG-R,Luteinizing hormone receptor,LHR,LSH-R,LHCGR,LCGR, LGR2, LHRHR,

    Tissue Specificity: Gonadal and thyroid cells.

    Background: The luteinizing hormone/choriogonadotropin receptor is a member of a subfamily of G protein-coupled receptors (GPCR) characterized by the presence of a large N-terminal extracellular domain containing several leucine-rich repeats (LRR). This glycoprotein hormone receptor family has been named the LRR-containing GPCR (LGR) family. The LHCGR gene contains 11 exons and spans approximately 80 kb and it is mapped to chromosome 2p21. In the ovary, theca, stromal, late-stage (luteinizing) granulosa, and luteal cells contain LHCGR. In the testes, Leydig cells contain LHCRG.

    Sequence Similarities: Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily.

    分子量
    78 kDa
    UniProt
    P22888
    途径
    Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, cAMP Metabolic Process, Glycosaminoglycan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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