EPH Receptor B3 抗体 (C-Term)
Quick Overview for EPH Receptor B3 抗体 (C-Term) (ABIN3042663)
抗原
See all EPH Receptor B3 (EPHB3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 982-998, C-Term
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原理
- Anti-Eph receptor B3/EPHB3 Antibody Picoband®
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序列
- SIQDMRLQMN QTLPVQV
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Eph receptor B3/EPHB3 Antibody (ABIN3042663). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Eph receptor B3, identical to the related rat and mouse sequences.
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亚型
- IgG
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anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibody
EPHB3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1B3 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibodyEPHB3 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 3F12 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-997) antibodyEPHB3 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 2G9 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 39-212) antibodyEPHB3 适用: 人 ELISA, IHC 宿主: 小鼠 Monoclonal 4A122D1 unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 650-700) antibodyEPHB3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 261-390) antibodyEPHB3 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) antibodyEPHB3 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 552-601) antibodyEPHB3 适用: 人, 犬, 马, Bat, 猴 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-EPH Receptor B3 (EPHB3) (AA 899-998) antibodyEPHB3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E12 unconjugated
anti-EPH Receptor B3 (EPHB3) antibodyEPHB3 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB16728 unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human, Rat, Mouse
Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
1. Bohme, B., Holtrich, U., Wolf, G., Luzius, H., Grzeschik, K.-H., Strebhardt, K., Rubsamen-Waigmann, H.PCR mediated detection of a new human receptor-tyrosine-kinase, HEK 2.Oncogene 8: 2857-2862, 1993. 2. Bohme, B., VandenBos, T., Cerretti, D. P., Park, L. S., Holtrich, U., Rubsamen-Waigmann, H., Strebhardt, K.Cell-cell adhesion mediated by binding of membrane-anchored ligand LERK-2 to the EPH-related receptor human embryonal kinase 2 promotes tyrosine kinase activity.J. Biol. Chem. 271: 24747-24752, 1996. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
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- EPH Receptor B3 (EPHB3)
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别名
- EPHB3
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背景
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Synonyms: Ephrin type-B receptor 3,2.7.10.1,EPH-like tyrosine kinase 2,EPH-like kinase 2,Embryonic kinase 2,EK2,hEK2,Tyrosine-protein kinase TYRO6,EPHB3,ETK2, HEK2, TYRO6,
Tissue Specificity: Ubiquitous.
Background: Ephrin Receptor EphB3, is also known as human embryo kinase2 (HEK2) or Eph-like tyrosine kinase2 (ETK2). HEK2, which is a member of the EPH/ELK family of tyrosine kinases, encodes a 998-amino acid polypeptide having a single putative transmembrane domain, a secretory signal sequence, and 2 fibronectin repeats. The EPHB3 gene is mapped to human chromosome 3q21-qter. HEK2 interacts with 2 ligands of EPH-related kinases (LERKs), namely, LERK2 (EFNB1) and LERK5 (EFNB2). Coincubation of HEK2- and LERK2-expressing cells induces cell-cell adhesion and aggregation. Additionally, coexpression of HEK2 and LERK2 results in reduced kinase activity of HEK2.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
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分子量
- 130 kDa
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UniProt
- P54753
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途径
- RTK signaling
抗原
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