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TBK1 抗体 (C-Term)

TBK1 适用: 人, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042649
发货至: 中国
  • 抗原 See all TBK1 抗体
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    抗原表位
    • 9
    • 8
    • 8
    • 6
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 577-590, C-Term
    适用
    • 70
    • 49
    • 27
    • 6
    • 6
    • 6
    • 6
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 73
    • 11
    • 1
    克隆类型
    • 70
    • 15
    多克隆
    标记
    • 45
    • 8
    • 8
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This TBK1 antibody is un-conjugated
    应用范围
    • 58
    • 42
    • 25
    • 10
    • 8
    • 7
    • 4
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase TBK1(TBK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    序列
    YNEEQIHKFD KQKL
    交叉反应 (详细)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    产品特性
    Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase TBK1(TBK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: TANK-binding kinase 1
    Protein Name: Serine/threonine-protein kinase TBK1
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence at the C-terminus of human NAK(577-590aa YNEEQIHKFDKQKL), identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product TBK1 Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, The detection limit for TBK1 is approximately 3 ng/lane under reducing conditions.
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    有效期
    12 months
  • 抗原
    TBK1 (TANK-Binding Kinase 1 (TBK1))
    别名
    TBK1 (TBK1 产品)
    别名
    nak antibody, t2k antibody, TBK1 antibody, wu:fk70c05 antibody, zgc:136548 antibody, NAK antibody, T2K antibody, 1200008B05Rik antibody, AI462036 antibody, AW048562 antibody, TANK binding kinase 1 L homeolog antibody, TANK binding kinase 1 antibody, TANK-binding kinase 1 antibody, tbk1.L antibody, TBK1 antibody, tbk1 antibody, Tbk1 antibody
    背景
    Serine/threonine-protein kinase TBK1, also called TANK-binding kinase 1 or NF-kappa-B-activating kinase is an enzyme that in humans is encoded by the TBK1 gene. The gene was assigned to human chromosome 12q14.2. Serine/threonine kinase plays an essential role in regulating inflammatory responses to foreign agents. TBK1 and NF-kappa-B signaling are essential in KRAS mutant tumors, and established a general approach for the rational identification of codependent pathways in cancer.

    Synonyms: EC 2.7.11.1 antibody|FLJ11330 antibody|NAK antibody|NF kappa B activating kinase antibody|NF kB activating kinase antibody|NF-kappa-B-activating kinase antibody|Serine/threonine protein kinase TBK 1 antibody|Serine/threonine protein kinase TBK1 antibody|Serine/threonine-protein kinase TBK1 antibody|T2K antibody|TANK antibody|TANK binding kinase 1 antibody|TANK-binding kinase 1 antibody|TBK 1 antibody|Tbk1 antibody|TBK1_HUMAN antibody|TRAF 2 antibody|TRAF2 antibody
    途径
    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, SARS-CoV-2 Protein Interactome
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