电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

c-FOS 抗体 (Middle Region)

c-Fos 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042631
发货至: 中国
  • 抗原 See all c-FOS (c-Fos) 抗体
    c-FOS (c-Fos) (c-Fos)
    抗原表位
    • 23
    • 21
    • 21
    • 18
    • 15
    • 15
    • 15
    • 7
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 170-187, Middle Region
    适用
    • 161
    • 139
    • 125
    • 11
    • 10
    • 9
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    人, 大鼠, 小鼠
    宿主
    • 170
    • 21
    • 6
    • 1
    • 1
    克隆类型
    • 173
    • 23
    • 1
    多克隆
    标记
    • 87
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This c-FOS antibody is un-conjugated
    应用范围
    • 161
    • 77
    • 77
    • 60
    • 34
    • 32
    • 28
    • 25
    • 17
    • 13
    • 9
    • 8
    • 6
    • 1
    • 1
    Western Blotting (WB)
    原理
    Anti-c-Fos Antibody Picoband®
    序列
    DQLEDEKSAL QTEIANLL
    交叉反应 (详细)
    No cross-reactivity with other proteins
    产品特性
    Anti-c-Fos Antibody (ABIN3042631). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
    纯化方法
    Immunogen affinity purified.
    免疫原
    A synthetic peptide corresponding to a sequence in the middle region of human c-Fos, identical to the related rat and mouse sequences.
    亚型
    IgG
    Top Product
    Discover our top product c-Fos Primary Antibody
  • 应用备注
    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse
    1. Barker, P. E., Rabin, M., Watson, M., Breg, W. R., Ruddle, F. H., Verma, I. M. : Human c-fos oncogene mapped within chromosomal region 14q21-q31. Proc. Nat. Acad. Sci. 81: 5826-5830, 1984. 2. Saez, E., Rutberg, S. E., Mueller, E., Oppenheim, H., Smoluk, J., Yuspa, S. H., Spiegelman, B. M. : c-fos is required for malignant progression of skin tumors. Cell 82: 721-732, 1995. 3. Grigoriadis, A. E., Wang, Z.-Q., Wagner, E. F. : Fos and bone cell development: lessons from a nuclear oncogene. Trends Genet. 11: :436-441, 1995.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    储存液
    Thimerosal (Merthiolate), Sodium azide
    注意事项
    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C,-20 °C
    储存方法
    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • Zheng, Wu, Gao, Wang: "Tumor suppressive role of miR-569 in lung cancer." in: Oncology letters, Vol. 15, Issue 4, pp. 4087-4092, (2018) (PubMed).

    Hou, Xia, Xiao, Wan, Zhao: "Neurotoxicity of intrathecal injections of dexmedetomidine into the rat spinal dorsal horn." in: Neural regeneration research, Vol. 7, Issue 23, pp. 1765-70, (2015) (PubMed).

    Qiu, Ding, Cui, Hu, Ding: "The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 343682, (2015) (PubMed).

    Liu, Peng, Lin, Luo, Jiang, Mo, Yung: "Effect of rhynchophylline on the expression of p-CREB and sc-Fos in triatum and hippocampal CA1 area of methamphetamine-induced conditioned place preference rats." in: Fitoterapia, Vol. 92, pp. 16-22, (2014) (PubMed).

    Zhang, Li, Xu, Mei, Zhang, Murong, Sun, Tong: "Changes of c-fos, malondialdehyde and lactate in brain tissue after global cerebral ischemia under different brain temperatures." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 354-8, (2014) (PubMed).

    Zhang, Zhang, Goldstein, Li, Ge, He, Ruiz: "The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model." in: Cell biochemistry and biophysics, Vol. 65, Issue 2, pp. 249-55, (2013) (PubMed).

    Li, Liang, Chen, Zhang, Lin, Huang: "L-dopa methyl ester attenuates amblyopia-induced neuronal injury in visual cortex of amblyopic cat." in: Gene, Vol. 527, Issue 1, pp. 115-22, (2013) (PubMed).

    Gong, Wang, Liang, Duan, Ouyang, Yu, Xu, Shen, Weng, Wu: "Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells." in: PLoS ONE, Vol. 7, Issue 10, pp. e47435, (2013) (PubMed).

    Peng, Zhang, Ren, Zhang, Wang: "Effect of ketamine administration on memory consolidation, p-CREB and c-fos expression in the hippocampal slices of minor rats." in: Molecular biology reports, Vol. 38, Issue 4, pp. 2401-7, (2011) (PubMed).

    Zhang, He, Goldstein, Ge, Wang, Ruiz: "The expression and significance of proto-oncogene c-fos in viral myocarditis." in: Virology journal, Vol. 7, pp. 285, (2010) (PubMed).

    Lou, Jiang, Li, Zhou, He, Lei, Li, Jia: "Herb medicine Gan-fu-kang attenuates liver injury in a rat fibrotic model." in: Journal of ethnopharmacology, Vol. 128, Issue 1, pp. 131-8, (2010) (PubMed).

    Xu, Tang, Li, Shi, Chen, Liang: "Positional and expressive alteration of prohibitin during the induced differentiation of human hepatocarcinoma SMMC-7721 cells." in: World journal of gastroenterology, Vol. 14, Issue 32, pp. 5008-14, (2008) (PubMed).

  • 抗原
    c-FOS (c-Fos) (c-Fos)
    别名
    FOS (c-Fos 产品)
    背景

    Synonyms: Proto-oncogene c-Fos,Cellular oncogene fos,G0/G1 switch regulatory protein 7,FOS,G0S7,

    Background: The human oncogene c-fos is cellular homolog of the transforming gene of Finkel-Biskis-Jinkins (FBJ) murine osteosarcoma virus which was mapped to a single human chromosome. c-Fos is encoded by the FOS gene. FOS was the first transcription factor identified that has a critical function in regulating the development of cells destined to form and maintain the skeleton. FOS is also a major component of the activator protein-1 (AP-1) transcription factor complex, which includes members of the JUN family. c-fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using transgenic and knockout mice, Grigoriadis et al. (1995) established a unique role for the proto-oncogene and nuclear transcription factor, Fos, in regulating the differentiation and activity of specific bone cell populations, both during normal development and in bone disease.

    Sequence Similarities: Belongs to the bZIP family. Fos subfamily.

    分子量
    37 kDa
    UniProt
    P01100
    途径
    S100 Proteins
You are here:
Chat with us!