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c-FOS 抗体 (Middle Region)

Cited in 12+ publications. This 兔 多克隆 anti-c-FOS antibody specifically detects c-FOS in WB. The antibody is reactive with 人, 大鼠 和 小鼠 samples.
产品编号 ABIN3042631
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for c-FOS 抗体 (Middle Region) (ABIN3042631)

抗原

See all c-FOS (c-Fos) 抗体
c-FOS (c-Fos) (c-Fos)

适用

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人, 大鼠, 小鼠

宿主

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克隆类型

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多克隆

标记

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This c-FOS antibody is un-conjugated

应用范围

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Western Blotting (WB)
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    AA 170-187, Middle Region

    原理

    Anti-c-Fos Antibody

    序列

    DQLEDEKSAL QTEIANLL

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-c-Fos Antibody (ABIN3042631). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence in the middle region of human c-Fos, identical to the related rat and mouse sequences.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human, Rat, Mouse

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    储存液

    Thimerosal (Merthiolate), Sodium azide

    注意事项

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • Zheng, Wu, Gao, Wang: "Tumor suppressive role of miR-569 in lung cancer." in: Oncology letters, Vol. 15, Issue 4, pp. 4087-4092, (2018) (PubMed).

    Hou, Xia, Xiao, Wan, Zhao: "Neurotoxicity of intrathecal injections of dexmedetomidine into the rat spinal dorsal horn." in: Neural regeneration research, Vol. 7, Issue 23, pp. 1765-70, (2015) (PubMed).

    Qiu, Ding, Cui, Hu, Ding: "The Expression Patterns of c-Fos and c-Jun Induced by Different Frequencies of Electroacupuncture in the Brain." in: Evidence-based complementary and alternative medicine : eCAM, Vol. 2015, pp. 343682, (2015) (PubMed).

    Liu, Peng, Lin, Luo, Jiang, Mo, Yung: "Effect of rhynchophylline on the expression of p-CREB and sc-Fos in triatum and hippocampal CA1 area of methamphetamine-induced conditioned place preference rats." in: Fitoterapia, Vol. 92, pp. 16-22, (2014) (PubMed).

    Zhang, Li, Xu, Mei, Zhang, Murong, Sun, Tong: "Changes of c-fos, malondialdehyde and lactate in brain tissue after global cerebral ischemia under different brain temperatures." in: Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban, Vol. 34, Issue 3, pp. 354-8, (2014) (PubMed).

    Zhang, Zhang, Goldstein, Li, Ge, He, Ruiz: "The effect of c-fos on acute myocardial infarction and the significance of metoprolol intervention in a rat model." in: Cell biochemistry and biophysics, Vol. 65, Issue 2, pp. 249-55, (2013) (PubMed).

    Li, Liang, Chen, Zhang, Lin, Huang: "L-dopa methyl ester attenuates amblyopia-induced neuronal injury in visual cortex of amblyopic cat." in: Gene, Vol. 527, Issue 1, pp. 115-22, (2013) (PubMed).

    Gong, Wang, Liang, Duan, Ouyang, Yu, Xu, Shen, Weng, Wu: "Soluble MOG35-55/I-A(b) dimers ameliorate experimental autoimmune encephalomyelitis by reducing encephalitogenic T cells." in: PLoS ONE, Vol. 7, Issue 10, pp. e47435, (2013) (PubMed).

    Peng, Zhang, Ren, Zhang, Wang: "Effect of ketamine administration on memory consolidation, p-CREB and c-fos expression in the hippocampal slices of minor rats." in: Molecular biology reports, Vol. 38, Issue 4, pp. 2401-7, (2011) (PubMed).

    Zhang, He, Goldstein, Ge, Wang, Ruiz: "The expression and significance of proto-oncogene c-fos in viral myocarditis." in: Virology journal, Vol. 7, pp. 285, (2010) (PubMed).

    Lou, Jiang, Li, Zhou, He, Lei, Li, Jia: "Herb medicine Gan-fu-kang attenuates liver injury in a rat fibrotic model." in: Journal of ethnopharmacology, Vol. 128, Issue 1, pp. 131-8, (2010) (PubMed).

    Xu, Tang, Li, Shi, Chen, Liang: "Positional and expressive alteration of prohibitin during the induced differentiation of human hepatocarcinoma SMMC-7721 cells." in: World journal of gastroenterology, Vol. 14, Issue 32, pp. 5008-14, (2008) (PubMed).

  • 抗原

    c-FOS (c-Fos) (c-Fos)

    别名

    FOS

    背景

    Synonyms: Proto-oncogene c-Fos,Cellular oncogene fos,G0/G1 switch regulatory protein 7,FOS,G0S7,

    Background: The human oncogene c-fos is cellular homolog of the transforming gene of Finkel-Biskis-Jinkins (FBJ) murine osteosarcoma virus which was mapped to a single human chromosome. c-Fos is encoded by the FOS gene. FOS was the first transcription factor identified that has a critical function in regulating the development of cells destined to form and maintain the skeleton. FOS is also a major component of the activator protein-1 (AP-1) transcription factor complex, which includes members of the JUN family. c-fos is a major nuclear target for signal transduction pathways involved in the regulation of cell growth, differentiation, and transformation. Using transgenic and knockout mice, Grigoriadis et al. (1995) established a unique role for the proto-oncogene and nuclear transcription factor, Fos, in regulating the differentiation and activity of specific bone cell populations, both during normal development and in bone disease.

    Sequence Similarities: Belongs to the bZIP family. Fos subfamily.

    分子量

    37 kDa

    UniProt

    P01100

    途径

    S100 Proteins
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