ATG7 抗体 (C-Term)
(2 references)Our Local Distributor
北京 101111
Quick Overview for ATG7 抗体 (C-Term) (ABIN3042570)
抗原
See all ATG7 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
原理
- Anti-Apg7/ATG7 Antibody
-
序列
- KVLDQYEREG FNFLAKVF
-
特异性
- No cross reactivity with other proteins.
-
交叉反应 （详细）
- No cross-reactivity with other proteins
-
预测反应
- different from the related mouse sequence by one amino acid,and from the related rat sequence by two amino acids.
-
产品特性
- Anti-Apg7/ATG7 Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat.
-
纯化方法
- Immunogen affinity purified.
-
免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Apg7, different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.
-
亚型
- IgG
-
-
anti-ATG7 Autophagy Related 7 (ATG7) (AA 540-569), (C-Term) antibody
ATG7 适用: 人, 小鼠 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB7474 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 477-698) antibodyATG7 适用: 小鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 22-51), (N-Term) antibodyATG7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7467 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibodyATG7 适用: 人, 小鼠, 大鼠 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 284-313) antibodyATG7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7469 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 494-523) antibodyATG7 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB7472 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (AA 558-703) antibodyATG7 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7D3E5 unconjugated
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (Biotin)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal Biotin
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (FITC)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal FITC
anti-ATG7 Autophagy Related 7 (ATG7) (N-Term) antibody (APC)ATG7 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal APC
-
-
应用备注
- Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
-
说明
-
Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
-
浓度
- 500 μg/mL
-
缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C,-20 °C
-
储存方法
-
Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
有效期
- 12 months
-
-
-
: "Erbin exerts a protective effect against inflammatory bowel disease by suppressing autophagic cell death." in: Oncotarget, Vol. 9, Issue 15, pp. 12035-12049, (2018) (PubMed).
: "Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta." in: Open biology, Vol. 6, Issue 7, (2017) (PubMed).
-
-
- ATG7 (ATG7 Autophagy Related 7 (ATG7))
-
别名
- ATG7
-
背景
-
Background: Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. It is mapped to 3p25.3. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, ATG7 can regulate p53-dependent cell cycle and cell death pathways.
Gene Full Name: autophagy related 7
Sequence Similarities: Belongs to the ubiquitin-conjugating enzyme family.
-
分子量
- 78 kDa
-
基因ID
- 10533
-
UniProt
- O95352
-
途径
- Response to Water Deprivation, Autophagy
抗原
-
