RAB8A 抗体 (C-Term)
Quick Overview for RAB8A 抗体 (C-Term) (ABIN3042554)
抗原
See all RAB8A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 170-183, C-Term
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原理
- Anti-Ras-related protein Rab-8A RAB8A Antibody Picoband®
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序列
- KAKMDKKLEG NSPQ
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-Ras-related protein Rab-8A RAB8A Antibody (ABIN3042554). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human RAB8A, identical to the related mouse and rat sequences.
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亚型
- IgG
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anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 108-207) antibody
RAB8A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3G1 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 68-207) antibodyRAB8A 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 7G8B11 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB22933 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 101-207) antibodyRAB8A 适用: 人, 小鼠, 大鼠 WB, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 8A4 unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (C-Term) antibodyRAB8A 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 小鸡, 马, 猴, 山羊, 豚鼠, Avian, Cat, 驴, Hamster, 兔 WB, IF, IHC (p), IHC (fro) 宿主: 山羊 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (Middle Region) antibodyRAB8A 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) antibodyRAB8A 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-RAB8A, Member RAS Oncogene Family (RAB8A) (AA 108-207) antibodyRAB8A 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 小鼠 Monoclonal 3G1 unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
1. "Entrez Gene: RAB8A RAB8A, member RAS oncogene family" 2. Tsang, W. Y., Bossard, C., Khanna, H., Peranen, J., Swaroop, A., Malhotra, V., Dynlacht, B. D. CP110 suppresses primary cilia formation through its interaction with CEP290, a protein deficiency in human ciliary disease. Dev. Cell 15: 187-197, 2008. 3. Nimmo ER, Sanders PG, Padua RA, Hughes D, Williamson R, Johnson KJ (October 1991). "The MEL gene: a new member of the RAB/YPT class of RAS-related genes". Oncogene 6 (8): 1347-51. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
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储存液
- Thimerosal (Merthiolate), Sodium azide
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注意事项
- This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))
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别名
- RAB8A
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背景
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Synonyms: Ras-related protein Rab-8A,Oncogene c-mel,RAB8A,MEL, RAB8,
Tissue Specificity: Expressed in brain, placenta and lung. .
Background: Ras-related protein Rab-8A is a protein that in humans is encoded by the RAB8A gene. It is mapped to 19p13.12. The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. RAB8A regulates cilia assembly by targeting and promoting fusion of vesicles near the ciliary membrane. This gene requires CEP290 for centrosome localization and that CEP290 regulates entry of RAB8A into the cilium during assembly of this organelle. RAB8A has been shown to interact with Optineurin and MAP4K2.
Sequence Similarities: Belongs to the beta-catenin family.
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分子量
- 24 kDa
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UniProt
- P61006
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途径
- M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome
抗原
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