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PLAT 抗体 (AA 366-562)

PLAT 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042504
发货至: 中国
  • 抗原 See all PLAT 抗体
    PLAT (Plasminogen Activator, Tissue (PLAT))
    抗原表位
    • 15
    • 15
    • 6
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    AA 366-562
    适用
    • 71
    • 70
    • 46
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠
    宿主
    • 99
    • 19
    • 9
    • 2
    • 1
    克隆类型
    • 112
    • 17
    多克隆
    标记
    • 54
    • 16
    • 12
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This PLAT antibody is un-conjugated
    应用范围
    • 97
    • 53
    • 35
    • 26
    • 26
    • 15
    • 14
    • 11
    • 9
    • 8
    • 6
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    • 1
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    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Tissue-type plasminogen activator(PLAT) detection. Tested with WB in Human,Mouse.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Tissue-type plasminogen activator(PLAT) detection. Tested with WB in Human,Mouse.
    Gene Name: plasminogen activator, tissue
    Protein Name: Tissue-type plasminogen activator
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human TPA recombinant protein (Position: H366-P562). Human TPA shares 83% and 84% amino acid (aa) sequence identity with mouse and rat TPA, respectively.
    亚型
    IgG
    Top Product
    Discover our top product PLAT Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, The detection limit for TPA is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    PLAT (Plasminogen Activator, Tissue (PLAT))
    别名
    PLAT (PLAT 产品)
    别名
    T-PA antibody, TPA antibody, AU020998 antibody, AW212668 antibody, D8Ertd2e antibody, tPA antibody, PATISS antibody, tpa antibody, Plat antibody, plat antibody, t-pa antibody, plasminogen activator, tissue type antibody, plasminogen activator, tissue antibody, chromosome 20 open reading frame 181 antibody, plasminogen activator, tissue L homeolog antibody, PLAT antibody, Plat antibody, plat antibody, C20orf181 antibody, plat.L antibody
    背景
    PLAT is also known as tPA. This gene encodes tissue-type plasminogen activator, a secreted serine protease which converts the proenzyme plasminogen to plasmin, a fibrinolytic enzyme. Tissue-type plasminogen activator is synthesized as a single chain which is cleaved by plasmin to a two chain disulfide linked protein. This enzyme plays a role in cell migration and tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysis which can result in thrombosis or embolism. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.

    Synonyms: Alteplase antibody|DKFZp686I03148 antibody|Plasminogen activator tissue antibody|Plasminogen activator tissue type antibody|Plasminogen Activator Tissue Type Isoform 1 Preproprotein antibody|PLAT antibody|Reteplase antibody|t PA antibody|T Plasminogen Activator antibody|t-PA antibody|T-plasminogen activator antibody|Tissue plasminogen activator (t PA) antibody|Tissue type plasminogen activator antibody|Tissue-type plasminogen activator chain B antibody|TPA antibody|TPA_HUMAN antibody|TPA1 antibody
    基因ID
    5327
    UniProt
    P00750
    途径
    Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome
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