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PD-1 抗体 (AA 101-288)

This anti-PD-1 antibody is a 兔多克隆 antibody detecting PD-1 in WB. Suitable for 人和小鼠.

Anti-PD1 Picoband antibody , All lanes: Anti PD1 at 0. (PD-1 抗体 (AA 101-288))

Anti-PD1 Picoband antibody , All lanes: Anti PD1 at 0. (PD-1 抗体 (AA 101-288))

2 images

产品编号 ABIN3042500

发货至: 中国

Quick Overview for PD-1 抗体 (AA 101-288) (ABIN3042500)

抗原

See all PD-1 (PDCD1) 抗体

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

适用

人, 小鼠

宿主

108
106
41
13
3
3
2
2
1
1

兔

克隆类型

多克隆

标记

This PD-1 antibody is un-conjugated

应用范围

148
109
94
59
46
32
27
27
20
18
13
13
13
10
9
5
4
4
4
4
3
2
1
1
1
1
1

Western Blotting (WB)

Discover our top product PDCD1 Primary Antibody

抗原表位
16

16

7

5

5

4

4

4

4

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 101-288

原理

Anti-PD1/PDCD1 Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-PD1/PDCD1 Antibody (ABIN3042500). Tested in WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human PD1 recombinant protein (Position: P101-L288). Human PD1 shares 59% amino acid (aa) sequence identity with mouse PD1.

亚型

IgG
anti-Programmed Cell Death 1 (PDCD1) (AA 201-288) antibody
PDCD1 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Programmed Cell Death 1 (PDCD1) (AA 41-132) antibody
PDCD1 适用: 人 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Programmed Cell Death 1 (PDCD1) (AA 192-288) antibody
PDCD1 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 8G5B12 unconjugated

anti-Programmed Cell Death 1 (PDCD1) (AA 192-288) antibody
PDCD1 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 3B3D9 unconjugated

anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibody
PDCD1 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 3E12A10 unconjugated

anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibody
PDCD1 适用: 人 FACS, WB, ELISA 宿主: 小鼠 Monoclonal 1D6F6 unconjugated

anti-Programmed Cell Death 1 (PDCD1) (AA 21-170) antibody
PDCD1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

anti-Programmed Cell Death 1 (PDCD1) (AA 1-288) antibody
PDCD1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated

anti-Programmed Cell Death 1 (PDCD1) antibody
PDCD1 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal PDCD1-2720 unconjugated

anti-Programmed Cell Death 1 (PDCD1) (AA 1-212) antibody
PDCD1 适用: 人 IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse
1. Barber, D. L., Wherry, E. J., Masopust, D., Zhu, B., Allison, J. P., Sharpe, A. H., Freeman, G. J., Ahmed, R. Restoring function in exhausted CD8 T cells during chronic viral infection. Nature 439: 682-687, 2006. 2. Dai, H., Wan, N., Zhang, S., Moore, Y., Wan, F., Dai, Z. Cutting edge: programmed death-1 defines CD8+CD122+ T cells as regulatory versus memory T cells. J. Immun. 185: 803-807, 2010. 3. Finger, L. R., Pu, J., Wasserman, R., Vibhakar, R., Louie, E., Hardy, R. R., Burrows, P. D., Billips, L. G. The human PD-1 gene: complete cDNA, genomic organization, and developmentally regulated expression in B cell progenitors. Gene 197: 177-187, 1997.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))

别名

PDCD1

背景

Synonyms: Programmed cell death protein 1,Protein PD-1,hPD-1,CD279,PDCD1,PD1,
Background: PDCD1 (Programmed cell death 1), also called PD1, encodes a cell surface receptor that is a member of the B7 superfamily involved in immunomodulation. This gene is mapped to 2q37.3. PDCD1 acts as an inhibitory molecule on T cells after interacting with its ligands PDL1 and PDL2. The PDCD1 gene contains 5 exons. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. Using flow cytometric analysis, It has been found that expression of PDCD1 was upregulated on CD16-positive and CD16-negative monocytes, but not on dendritic cells, in viremic HIV-positive patients, but not in highly active antiretroviral therapy (HAART)-treated HIV-positive patients. PDCD1 upregulation in monocytes was induced by microbial Toll-like receptor ligands and inflammatory cytokines.

分子量

65 kDa

基因ID

5133

UniProt

Q15116

途径

Cancer Immune Checkpoints

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