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HSF4 抗体 (N-Term)

This anti-HSF4 antibody is a 兔 多克隆 antibody detecting HSF4 in WB. Suitable for 人.
产品编号 ABIN3042461
发货至: 中国

Quick Overview for HSF4 抗体 (N-Term) (ABIN3042461)

抗原

See all HSF4 抗体
HSF4 (Heat Shock Transcription Factor 4 (HSF4))

适用

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宿主

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克隆类型

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多克隆

标记

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This HSF4 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 149-185, N-Term

    原理

    Anti-HSF4 Antibody Picoband®

    序列

    VQESTEARLR ELRQQNEILW REVVTLRQSH GQQHRVI

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-HSF4 Antibody Picoband® (ABIN3042461). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the N-terminus of human HSF4, different from the related mouse sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human
    1. Bu L, Jin Y, Shi Y, Chu R, Ban A, Eiberg H, Andres L, Jiang H, Zheng G, Qian M, Cui B, Xia Y, Liu J, Hu L, Zhao G, Hayden MR, Kong X (Jun 2002). "Mutant DNA-binding domain of HSF4 is associated with autosomal dominant lamellar and Marner cataract". Nat Genet 31 (3): 276-8. 2. Nakai A, Tanabe M, Kawazoe Y, Inazawa J, Morimoto RI, Nagata K (Jan 1997). "HSF4, a new member of the human heat shock factor family which lacks properties of a transcriptional activator". Mol Cell Biol 17 (1): 469-81. 3. Tanabe M, Sasai N, Nagata K, Liu XD, Liu PC, Thiele DJ, Nakai A (Nov 1999). "The mammalian HSF4 gene generates both an activator and a repressor of heat shock genes by alternative splicing". J Biol Chem 274(39): 27845-56.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • 抗原

    HSF4 (Heat Shock Transcription Factor 4 (HSF4))

    别名

    HSF4

    背景

    Synonyms: Heat shock factor protein 4,HSF 4,hHSF4,Heat shock transcription factor 4,HSTF 4,HSF4,

    Tissue Specificity: Expressed in heart, skeletal muscle, eye and brain, and at much lower levels in some other tissues. .

    Background: Heat shock factor protein 4 is a protein that in humans is encoded by the HSF4 gene. It is mapped to 16q21. Heat-shock transcription factors (HSFs) activate heat-shock response genes under conditions of heat or other stresses. HSF4 lacks the carboxyl-terminal hydrophobic repeat which is shared among all vertebrate HSFs and has been suggested to be involved in the negative regulation of DNA binding activity. Two alternatively spliced transcripts encoding distinct isoforms and possessing different transcriptional activity have been described.

    Sequence Similarities: Contains 1 HMG box DNA-binding domain.

    分子量

    53 kDa

    基因ID

    3299

    途径

    MAPK Pathway
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