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HDAC6 抗体 (N-Term)

This anti-HDAC6 antibody is a 兔多克隆 antibody detecting HDAC6 in WB 和 FACS. Suitable for 人, 小鼠和大鼠.

Observed bind size: 160KD (HDAC6 抗体 (N-Term))

1 image

产品编号 ABIN3042440

发货至: 中国

Quick Overview for HDAC6 抗体 (N-Term) (ABIN3042440)

抗原

See all HDAC6 抗体

HDAC6 (Histone Deacetylase 6 (HDAC6))

适用

122
43
30
8
5
5
4
3
3
2
1
1
1

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

73
8
4
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
1
1

This HDAC6 antibody is un-conjugated

应用范围

100
41
36
28
27
26
19
19
17
10
6
5
3
2
2
1
1

Western Blotting (WB), Flow Cytometry (FACS)

Discover our top product HDAC6 Primary Antibody

抗原表位
26

15

11

9

6

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 137-169, N-Term

原理

Anti-HDAC6 Antibody Picoband®

序列

EKEELMLVHS LEYIDLMETT QYMNEGELRV LAD

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-HDAC6 Antibody Picoband® (ABIN3042440). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

A synthetic peptide corresponding to a sequence at the N-terminus of human HDAC6, different from the related mouse sequence by one amino acid.

亚型

IgG
anti-Histone Deacetylase 6 (HDAC6) (AA 560-811) antibody
HDAC6 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 6 (HDAC6) antibody
HDAC6 适用: 人, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1B3 unconjugated

anti-Histone Deacetylase 6 (HDAC6) antibody
HDAC6 适用: 人, 大鼠, 猴, 犬 WB, IF, FACS 宿主: 小鼠 Monoclonal 4C5 unconjugated

anti-Histone Deacetylase 6 (HDAC6) (AA 1-200) antibody
HDAC6 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 6 (HDAC6) (AA 166-348) antibody
HDAC6 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 6 (HDAC6) (AA 1128-1215) antibody
HDAC6 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E2 unconjugated

anti-Histone Deacetylase 6 (HDAC6) antibody
HDAC6 适用: 人 WB, ELISA, IP, ICC, ICFC 宿主: 小鼠 Monoclonal 236 unconjugated

anti-Histone Deacetylase 6 (HDAC6) (AA 69-118) antibody
HDAC6 适用: 人, 小鼠, 猴, 兔, 马, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Histone Deacetylase 6 (HDAC6) (C-Term) antibody
Verified HDAC6 适用: 人 IHC, ELISA, IF, FACS 宿主: 山羊 Polyclonal unconjugated

anti-Histone Deacetylase 6 (HDAC6) antibody
HDAC6 适用: 人 IF, IP, FACS 宿主: 小鼠 Monoclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
1. Bertos, N. R., Gilquin, B., Chan, G. K. T., Yen, T. J., Khochbin, S., Yang, X.-J. Role of the tetradecapeptide repeat domain of human histone deacetylase 6 in cytoplasmic retention. J. Biol. Chem. 279: 48246-48254, 2004. 2. Grozinger, C. M., Hassig, C. A., Schreiber, S. L. Three proteins define a class of human histone deacetylases related to yeast Hda1p. Proc. Nat. Acad. Sci. 96: 4868-4873, 1999.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

HDAC6 (Histone Deacetylase 6 (HDAC6))

别名

HDAC6

背景

Synonyms: Histone deacetylase 6,HD6,3.5.1.98,HDAC6,KIAA0901,JM21,
Tissue Specificity: Liver.
Background: HDAC6, also called KIAA0901, is a member belongs to class II of the histone deacetylase/acuc/apha family of proteins that is an enzyme that in humans is encoded by the HDAC6 gene. The HDAC6 gene is mapped to chromosome Xp11.23. HDAC6 contains an internal duplication of two catalytic domains which appear to function independently of each other. The protein possesses histone deacetylase activity and represses transcription. HDAC6 functions as a tubulin deacetylase. And it is localized exclusively in the cytoplasm, where it associates with microtubules and localizes with the microtubule motor complex. HDAC6 could bind both polyubiquitinated misfolded proteins and dynein motors, thereby recruiting misfolded protein cargo to dynein motors for transport to aggresomes. Furthermore, expression of HDAC6 was sufficient to rescue degeneration associated with UPS dysfunction in vivo in an autophagy-dependent manner. HDAC6 is a central component of the stress response that regulates SG formation and potentially contributes to control of RNA metabolism and translation.
Sequence Similarities: Contains 1 HMG box DNA-binding domain.

分子量

160 kDa

基因ID

10013

途径

Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling

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