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- 抗原 See all GFRA1 抗体
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
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抗原表位
- AA 25-227
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GFRA1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC)
- 原理
- Anti-GDNF Receptor alpha 1/GFRA1 Antibody Picoband®
- 交叉反应 （详细）
- No cross-reactivity with other proteins
- 产品特性
- Anti-GDNF Receptor alpha 1/GFRA1 Antibody Picoband® (ABIN3042422). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
- 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human GFRA1 recombinant protein (Position: D25-Q227). Human GFRA1 shares 97% amino acid (aa) sequence identity with both mouse and rat GFRA1.
- 亚型
- IgG
- Top Product
- Discover our top product GFRA1 Primary Antibody
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anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 239-350) antibody
GFRA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 25-280) antibodyGFRA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 351-429) antibodyGFRA1 适用: 人, 小鼠, 山羊 WB, ELISA, FACS, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 230-385) antibodyGFRA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 32-119) antibodyGFRA1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4D8 unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 32-119) antibodyGFRA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) antibodyGFRA1 适用: 人 WB, ELISA, IF 宿主: 小鸡 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 72-83), (Extracellular) antibodyGFRA1 适用: 大鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 381-415), (C-Term) antibodyGFRA1 适用: 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB50601 unconjugated
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- 应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
1. Gorodinsky A, Zimonjic DB, Popescu NC, Milbrandt J (March 1998). "Assignment of the GDNF family receptor alpha-1 (GFRA1) to human chromosome band 10q26 by in situ hybridization". Cytogenet Cell Genet 78 (3-4): 289-90. 2. Angrist M, Jing S, Bolk S, Bentley K, Nallasamy S, Halushka M, Fox GM, Chakravarti A (June 1998). "Human GFRA1: cloning, mapping, genomic structure, and evaluation as a candidate gene for Hirschsprung disease susceptibility". Genomics 48 (3): 354-62. 3. "Entrez Gene: GFRA1 GDNF family receptor alpha 1" - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C,-20 °C
- 储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- 抗原
- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
- 别名
- GFRA1 (GFRA1 产品)
- 背景
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Synonyms: GDNF family receptor alpha-1;GDNF receptor alpha-1;GDNFR-alpha-1;GFR-alpha-1;RET ligand 1;TGF-beta-related neurotrophic factor receptor 1;GFRA1;GDNFRA, RETL1, TRNR1;
Tissue Specificity: T-cells and endothelial cells.
Background: GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor or GFRA1, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to chromosome 10q25.3. The protein encoded by this gene is a member of the GDNF receptor family. GFRA1 is released by neuronal cells, Schwann cells, and injured sciatic nerve. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is also a candidate gene for Hirschsprung disease. Soluble GFRA1 mediates robust recruitment of RET to lipid rafts via a mechanism requiring the RET tyrosine kinase.
Sequence Similarities: Belongs to the glutamate--cysteine ligase type 3 family.
- 分子量
- 51 kDa
- 基因ID
- 14585
- UniProt
- P56159
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