GFRA1 抗体 (AA 25-227)
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Quick Overview for GFRA1 抗体 (AA 25-227) (ABIN3042422)
抗原
See all GFRA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 25-227
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原理
- Anti-GDNF Receptor alpha 1/GFRA1 Antibody
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-GDNF Receptor alpha 1/GFRA1 Antibody (ABIN3042422). Tested in IHC, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human GFRA1 recombinant protein (Position: D25-Q227). Human GFRA1 shares 97% amino acid (aa) sequence identity with both mouse and rat GFRA1.
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亚型
- IgG
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anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 25-280) antibody
GFRA1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 239-350) antibodyGFRA1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 351-429) antibodyGFRA1 适用: 人, 小鼠 WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 230-385) antibodyGFRA1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 32-119) antibodyGFRA1 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1G4 unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 32-119) antibodyGFRA1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 4D8 unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 369-382) antibodyGFRA1 适用: 人, 小鼠, 大鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) antibodyGFRA1 适用: 人 WB, ELISA, IF 宿主: 小鸡 Polyclonal unconjugated
anti-GDNF Family Receptor alpha 1 (GFRA1) (AA 72-83), (Extracellular) antibodyGFRA1 适用: 大鼠 WB, IHC, IF, IC, LCI 宿主: 兔 Polyclonal unconjugated
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human
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说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))
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别名
- GFRA1
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背景
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Synonyms: GDNF family receptor alpha-1;GDNF receptor alpha-1;GDNFR-alpha-1;GFR-alpha-1;RET ligand 1;TGF-beta-related neurotrophic factor receptor 1;GFRA1;GDNFRA, RETL1, TRNR1;
Tissue Specificity: T-cells and endothelial cells.
Background: GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor or GFRA1, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to chromosome 10q25.3. The protein encoded by this gene is a member of the GDNF receptor family. GFRA1 is released by neuronal cells, Schwann cells, and injured sciatic nerve. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is also a candidate gene for Hirschsprung disease. Soluble GFRA1 mediates robust recruitment of RET to lipid rafts via a mechanism requiring the RET tyrosine kinase.
Sequence Similarities: Belongs to the glutamate--cysteine ligase type 3 family.
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分子量
- 51 kDa
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基因ID
- 14585
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UniProt
- P56159
抗原
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