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FURIN 抗体 (AA 591-794)

FURIN 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042409
发货至: 中国
  • 抗原 See all FURIN 抗体
    FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
    抗原表位
    • 15
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 591-794
    适用
    • 39
    • 36
    • 16
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    宿主
    • 53
    • 3
    • 3
    克隆类型
    • 45
    • 14
    多克隆
    标记
    • 26
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This FURIN antibody is un-conjugated
    应用范围
    • 28
    • 18
    • 18
    • 13
    • 13
    • 9
    • 8
    • 6
    • 4
    • 4
    • 3
    Western Blotting (WB)
    原理
    Rabbit IgG polyclonal antibody for Furin(FURIN) detection. Tested with WB in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Furin(FURIN) detection. Tested with WB in Human.
    Gene Name: furin (paired basic amino acid cleaving enzyme)
    Protein Name: Furin
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human Furin recombinant protein (Position: T591-L794). Human Furin shares 88% amino acid (aa) sequence identity with both mouse and rat Furin.
    亚型
    IgG
    Top Product
    Discover our top product FURIN Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Furin is approximately 0.25 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    FURIN (Furin (Paired Basic Amino Acid Cleaving Enzyme) (FURIN))
    别名
    FURIN (FURIN 产品)
    别名
    FURIN antibody, furin antibody, si:dkey-281a24.5 antibody, FUR antibody, LOC100220259 antibody, PACE antibody, spc1 antibody, xfurin antibody, MGC82710 antibody, PCSK3 antibody, SPC1 antibody, 9130404I01Rik antibody, Fur antibody, Pcsk3 antibody, Pace antibody, furin, paired basic amino acid cleaving enzyme antibody, furin (paired basic amino acid cleaving enzyme) a antibody, furin (paired basic amino acid cleaving enzyme) b antibody, furin, paired basic amino acid cleaving enzyme L homeolog antibody, furin (paired basic amino acid cleaving enzyme) antibody, FURIN antibody, furina antibody, furinb antibody, furin antibody, furin.L antibody, Furin antibody
    背景
    Furin(Fur), also known as PACE, is a protein that in humans is encoded by the FURIN gene. The protein encoded by this gene is an enzyme which belongs to the subtilisin-like proprotein convertase family. The Furin gene is located approximately 1 kb upstream of the FES gene on chromosome 15q25-q26. This gene is thought to play a role in tumor progression. Furin is one of the proteases responsible for the proteolytic cleavage of HIV envelope polyprotein precursor gp160 to gp120 and gp41 prior to viral assembly. Furin is enriched in the Golgi apparatus, where it functions to cleave other proteins into their mature/active forms. Expression of furin in T-cells is required for maintenance of peripheral immune tolerance.

    Synonyms: Dibasic processing enzyme antibody|Dibasic-processing enzyme antibody|FES upstream region antibody|FUR antibody|FURIN antibody|Furin membrane associated receptor protein antibody|FURIN_HUMAN antibody|PACE antibody|Paired basic amino acid residue cleaving enzyme antibody|Paired basic amino acid residue-cleaving enzyme antibody|PCSK3 antibody|Proprotein convertase subtilisin/kexin type 3 antibody|SPC1 antibody
    基因ID
    5045
    UniProt
    P09958
    途径
    Notch Signaling, Neurotrophin Signaling Pathway
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