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FRZB 抗体 (AA 176-325)

FRZB 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN3042406
发货至: 中国
  • 抗原 See all FRZB 抗体
    FRZB (Frizzled-Related Protein (FRZB))
    抗原表位
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 176-325
    适用
    • 38
    • 21
    • 14
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 29
    • 6
    • 5
    • 1
    • 1
    克隆类型
    • 37
    • 5
    多克隆
    标记
    • 25
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This FRZB antibody is un-conjugated
    应用范围
    • 27
    • 14
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    原理
    Rabbit IgG polyclonal antibody for Secreted frizzled-related protein 3(FRZB) detection. Tested with WB, ELISA in Human.
    交叉反应 (详细)
    No cross reactivity with other proteins.
    产品特性
    Rabbit IgG polyclonal antibody for Secreted frizzled-related protein 3(FRZB) detection. Tested with WB, ELISA in Human.
    Gene Name: frizzled-related protein
    Protein Name: Secreted frizzled-related protein 3
    纯化方法
    Immunogen affinity purified.
    免疫原
    E.coli-derived human FRZB recombinant protein (Position: E176-N325). Human FRZB shares 90% amino acid (aa) sequence identity with mouse FRZB.
    亚型
    IgG
    Top Product
    Discover our top product FRZB Primary Antibody
  • 应用备注
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for FRZB is approximately 0.1 ng/lane under reducing conditions.
    ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human

    Notes: Other applications have not been tested. Optimal dilutions should be determined by end users.
    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    浓度
    500 μg/mL
    缓冲液
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • 抗原
    FRZB (Frizzled-Related Protein (FRZB))
    别名
    FRZB (FRZB 产品)
    别名
    Frp antibody, Sfrp3 antibody, frezzled antibody, fritz antibody, frzb-1 antibody, FRE antibody, FRITZ antibody, FRP-3 antibody, FRZB-1 antibody, FRZB-PEN antibody, FRZB1 antibody, FZRB antibody, OS1 antibody, SFRP3 antibody, SRFP3 antibody, hFIZ antibody, Frzb-1 antibody, frizzled-related protein antibody, Frzb antibody, FRZB antibody
    背景
    FRZB is also known as FRE or OS1. The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. FRZB is a Wnt-binding protein especially important in embryonic development. It is a competitor for the cell-surface G-protein receptor Frizzled. FRZB is localized in the extracellular plasma membrane. Unlike frizzled, frzb lacks the 7 transmembrane domains normally found in G-protein-coupled receptors. It is still considered a homolog of frizzled because it contains a Cysteine Rich Domain (CRD), and because of its intracellular C-terminus which is crucial for signaling.

    Synonyms: FIZ antibody|FRE antibody|Frezzled antibody|Fritz antibody|Frizzled-related protein 1 antibody|FRP antibody|FrzB 1 antibody|FRZB antibody|FRZB1 antibody|OTTMUSP00000014350 antibody|RP23-33L19.1 antibody|Secreted frizzled related protein 3 [Precursor] antibody|Secreted frizzled related sequence protein 3 antibody|sFRP 3 antibody|SFRP antibody
    基因ID
    2487
    UniProt
    Q92765
    途径
    WNT signaling, Positive Regulation of fat Cell Differentiation
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