FRZB 抗体 (AA 176-325)
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- 抗原 See all FRZB 抗体
- FRZB (Frizzled-Related Protein (FRZB))
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抗原表位
- AA 176-325
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FRZB antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA
- 原理
- Rabbit IgG polyclonal antibody for Secreted frizzled-related protein 3(FRZB) detection. Tested with WB, ELISA in Human.
- 交叉反应 (详细)
- No cross reactivity with other proteins.
- 产品特性
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Rabbit IgG polyclonal antibody for Secreted frizzled-related protein 3(FRZB) detection. Tested with WB, ELISA in Human.
Gene Name: frizzled-related protein
Protein Name: Secreted frizzled-related protein 3 - 纯化方法
- Immunogen affinity purified.
- 免疫原
- E.coli-derived human FRZB recombinant protein (Position: E176-N325). Human FRZB shares 90% amino acid (aa) sequence identity with mouse FRZB.
- 亚型
- IgG
- Top Product
- Discover our top product FRZB Primary Antibody
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- 应用备注
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for FRZB is approximately 0.1 ng/lane under reducing conditions.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Other applications have not been tested. Optimal dilutions should be determined by end users. - 说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- 浓度
- 500 μg/mL
- 缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeated freezing and thawing.
- 储存条件
- 4 °C/-20 °C
- 储存方法
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- 抗原
- FRZB (Frizzled-Related Protein (FRZB))
- 别名
- FRZB (FRZB 产品)
- 背景
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FRZB is also known as FRE or OS1. The protein encoded by this gene is a secreted protein that is involved in the regulation of bone development. Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility. FRZB is a Wnt-binding protein especially important in embryonic development. It is a competitor for the cell-surface G-protein receptor Frizzled. FRZB is localized in the extracellular plasma membrane. Unlike frizzled, frzb lacks the 7 transmembrane domains normally found in G-protein-coupled receptors. It is still considered a homolog of frizzled because it contains a Cysteine Rich Domain (CRD), and because of its intracellular C-terminus which is crucial for signaling.
Synonyms: FIZ antibody|FRE antibody|Frezzled antibody|Fritz antibody|Frizzled-related protein 1 antibody|FRP antibody|FrzB 1 antibody|FRZB antibody|FRZB1 antibody|OTTMUSP00000014350 antibody|RP23-33L19.1 antibody|Secreted frizzled related protein 3 [Precursor] antibody|Secreted frizzled related sequence protein 3 antibody|sFRP 3 antibody|SFRP antibody - 基因ID
- 2487
- UniProt
- Q92765
- 途径
- WNT signaling, Positive Regulation of fat Cell Differentiation
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