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FOXO3 抗体 (AA 471-673)

Name: FOXO3 抗体 (AA 471-673)
SKU: ABIN3042404
Availability: OutOfStock

FOXO3 适用: 人, 大鼠 WB, IHC, IF, ICC, FACS 宿主: 兔 Polyclonal unconjugated

Anti- FOXO3A antibody, Western blotting All lanes: Anti FOXO3A at 0. (FOXO3 抗体 (AA 471-673))

Anti- FOXO3A antibody,IHC(P) IHC(P): Human Intestinal Cancer Tissue (FOXO3 抗体 (AA 471-673))

IHC

Anti- FOXO3A antibody,IHC(P) IHC(P): Human Lung Cancer Tissue (FOXO3 抗体 (AA 471-673))

IHC

4 images

产品编号 ABIN3042404

发货至: 中国

Datasheet as PDF

抗原 See all FOXO3 抗体

FOXO3 (Forkhead Box O3 (FOXO3))
抗原表位
38

9

8

8

8

7

7

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 471-673
适用
124

81

71

9

7

6

6

5

5

4

3

3

2

2

2

1
人, 大鼠
宿主
125

6

1

1
兔
Compatible Secondaries
克隆类型
110

23
多克隆
标记
79

7

4

4

4

4

4

4

4

3

3

2

1

1

1

1

1

1

1

1

1

1

1
This FOXO3 antibody is un-conjugated
应用范围
97

54

52

33

22

21

21

15

14

14

4

3

2

2

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Flow Cytometry (FACS)

原理

Anti-FOXO3A Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-FOXO3A Antibody Picoband® (ABIN3042404). Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human FOXO3A recombinant protein (Position: Q471-G673). Human FOXO3A shares 97% amino acid (aa) sequence identity with mouse FOXO3A.

亚型

IgG

Top Product

Discover our top product FOXO3 Primary Antibody
anti-Forkhead Box O3 (FOXO3) (pSer253) antibody
FOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (AA 394-672) antibody
FOXO3 适用: 小鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (C-Term) antibody
Verified FOXO3 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (pSer318), (pSer321) antibody
FOXO3 适用: 人, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (C-Term) antibody
KO Validated FOXO3 适用: 人 WB, IF, IHC (p), IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (N-Term) antibody
FOXO3 适用: 人, 小鼠, 大鼠, 犬, Cow, Pig, 绵羊, 兔, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) antibody
FOXO3 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Monoclonal 1E2 unconjugated Recombinant Antibody

anti-Forkhead Box O3 (FOXO3) (N-Term) antibody
FOXO3 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibody
FOXO3 适用: 人 ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1E11 unconjugated

anti-Forkhead Box O3 (FOXO3) (AA 361-460) antibody
FOXO3 适用: 人 WB, ELISA, IF, IHC (p) 宿主: 小鼠 Monoclonal 1F6 unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human, Rat
Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human
Flow Cytometry(Fixed), 1-3 μg/1x10⁶ cells, Human
1. Anderson MJ, Viars CS, Czekay S, Cavenee WK, Arden KC (January 1998). "Cloning and characterization of three human forkhead genes that comprise an FKHR-like gene subfamily". Genomics 47 (2): 187-99. 2. Brunet A, Bonni A, Zigmond MJ, Lin MZ, Juo P, Hu LS, Anderson MJ, Arden KC, Blenis J, Greenberg ME (March 1999). "Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor". Cell 96 (6): 857-68. 3. Ekoff M, Kaufmann T, Engström M, Motoyama N, Villunger A, Jönsson JI, Strasser A, Nilsson G (November 2007). "The BH3-only protein Puma plays an essential role in cytokine deprivation induced apoptosis of mast cells". Blood 110 (9): 3209-17.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
抗原

FOXO3 (Forkhead Box O3 (FOXO3))

别名

FOXO3 (FOXO3 产品)

背景

Synonyms: Forkhead box protein O3,AF6q21 protein,Forkhead in rhabdomyosarcoma-like 1,FOXO3,FKHRL1, FOXO3A,
Tissue Specificity: Ubiquitous. .
Background: Forkhead box O3, also known as FKHRL1 or FOXO3a, is a human protein encoded by the FOXO3 gene. FOXO3 belongs to the O subclass of the forkhead family of transcription factors which are characterized by a distinct fork head DNA-binding domain. It is mapped to 6q21. This protein likely functions as a trigger for apoptosis through upregulation of genes necessary for cell death, such as Bim and PUMA, or downregulation of anti-apoptotic proteins such as FLIP. In mammals FOXO3 regulates the resistance of cells to stress by inducing DNA repair and thereby may also affect organismal life span. In addition, it is thought that FOXO3 is also involved in protection from oxidative stress by upregulating antioxidants such as catalase and MnSOD.
Sequence Similarities: Contains 1 fork-head DNA-binding domain.

分子量

80-90 kDa

基因ID

2309

UniProt

O43524

途径

Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Carbohydrate Homeostasis