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FGF1 抗体 (AA 22-146)

Cited in 3+ publications. This 兔 多克隆 anti-FGF1 antibody specifically detects FGF1 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN3042389
发货至: 中国
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中国
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Quick Overview for FGF1 抗体 (AA 22-146) (ABIN3042389)

抗原

See all FGF1 抗体
FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

适用

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宿主

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克隆类型

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多克隆

标记

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This FGF1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 22-146

    原理

    Anti-FGF1 Antibody

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-FGF1 Antibody (ABIN3042389). Tested in WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    纯化方法

    Immunogen affinity purified.

    免疫原

    E.coli-derived human FGF1 recombinant protein (Position: N22-L146). Human FGF1 shares 97% amino acid (aa) sequence identity with both mouse and rat FGF1.

    亚型

    IgG
  • 应用备注

    Western blot, 0.1-0.5 μg/mL, Human

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Zhang, Wang, Wang, Jiang, Yu, Chong, Fu: "Ferulic acid ameliorates nerve injury induced by cerebral ischemia in rats." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 972-976, (2015) (PubMed).

    Zhou, Ren, Zhu, Yan, Wang, Song, Li, Ouyang, Pang: "Construction of a recombinant human FGF1 expression vector for mammary gland-specific expression in human breast cancer cells." in: Molecular and cellular biochemistry, Vol. 354, Issue 1-2, pp. 39-46, (2011) (PubMed).

    Gu, Zhang, Wu, Xu, Cui, Yang, Zhao, Sun: "Differential expression of decorin, EGFR and cyclin D1 during mammary gland carcinogenesis in TA2 mice with spontaneous breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 6, (2010) (PubMed).

  • 抗原

    FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))

    别名

    FGF1

    背景

    Synonyms: Fibroblast growth factor 1,FGF-1,Acidic fibroblast growth factor,aFGF,Endothelial cell growth factor,ECGF,Heparin-binding growth factor 1,HBGF-1,FGF1,FGFA,

    Tissue Specificity: Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. .

    Background: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor.

    Sequence Similarities: Belongs to the heparin-binding growth factors family.

    分子量

    36 kDa

    基因ID

    2246

    UniProt

    P05230

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
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