FGF1 抗体 (AA 22-146)
(3 references)Quick Overview for FGF1 抗体 (AA 22-146) (ABIN3042389)
抗原
See all FGF1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 22-146
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原理
- Anti-FGF1 Antibody Picoband®
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-FGF1 Antibody Picoband® (ABIN3042389). Tested in WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- E.coli-derived human FGF1 recombinant protein (Position: N22-L146). Human FGF1 shares 97% amino acid (aa) sequence identity with both mouse and rat FGF1.
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亚型
- IgG
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anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 46-155) antibody
FGF1 适用: 人 WB, ELISA, IP, IF, IHC (p) 宿主: 小鼠 Monoclonal 2E12 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal C2 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 46-155) antibodyFGF1 适用: 人 WB, ELISA, IF, PLA 宿主: 小鼠 Monoclonal 3F5 unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) antibodyFGF1 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-155) antibodyFGF1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 5-30) antibodyFGF1 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 16-80) antibodyFGF1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 12-151) antibodyFGF1 适用: Pig WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fibroblast Growth Factor 1 (Acidic) (FGF1) (AA 2-155) antibodyFGF1 适用: 绵羊 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human
1. Le Beau, M. M., Espinosa, R., III, Neuman, W. L., Stock, W., Roulston, D., Larson, R. A., Keinanen, M., Westbrook, C. A. : Cytogenetic and molecular delineation of the smallest commonly deleted region of chromosome 5 in malignant myeloid diseases. Proc. Nat. Acad. Sci. 90: 5484-5488, 1993. 2. Mergia, A., Eddy, R., Abraham, J. A., Fiddes, J. C., Shows, T. B. : The genes for basic and acidic fibroblast growth factors are on different human chromosomes. Biochem. Biophys. Res. Commun. 138: 644-651, 1986. 3. Burgess, W. H., Mehlman, T., Marshak, D. R., Fraser, B. A., Maciag, T. : Structural evidence that endothelial cell growth factor beta is the precursor of both endothelial cell growth factor alpha and acidic fibroblast growth factor. Proc. Nat. Acad. Sci. 83: 7216-7220, 1986. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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: "Ferulic acid ameliorates nerve injury induced by cerebral ischemia in rats." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 972-976, (2015) (PubMed).
: "Construction of a recombinant human FGF1 expression vector for mammary gland-specific expression in human breast cancer cells." in: Molecular and cellular biochemistry, Vol. 354, Issue 1-2, pp. 39-46, (2011) (PubMed).
: "Differential expression of decorin, EGFR and cyclin D1 during mammary gland carcinogenesis in TA2 mice with spontaneous breast cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 29, pp. 6, (2010) (PubMed).
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: "Ferulic acid ameliorates nerve injury induced by cerebral ischemia in rats." in: Experimental and therapeutic medicine, Vol. 9, Issue 3, pp. 972-976, (2015) (PubMed).
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- FGF1 (Fibroblast Growth Factor 1 (Acidic) (FGF1))
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别名
- FGF1
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背景
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Synonyms: Fibroblast growth factor 1,FGF-1,Acidic fibroblast growth factor,aFGF,Endothelial cell growth factor,ECGF,Heparin-binding growth factor 1,HBGF-1,FGF1,FGFA,
Tissue Specificity: Predominantly expressed in kidney and brain. Detected at much lower levels in heart and skeletal muscle. .
Background: Fibroblast growth factor 1 (acidic), also known as FGF1/ECGF/HBGF1, is a human gene which is mapped to 5q31. The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. Acidic fibroblast growth factor is derived from beta-endothelial cell growth factor (ECGFB) by posttranslational processing. It acts as a mitogen for a variety of mesoderm- and neuroectoderm-derived cells in vitro, thus is thought to be involved in organogenesis. This protein functions as a modifier of endothelial cell migration and proliferation, as well as an angiogenic factor.
Sequence Similarities: Belongs to the heparin-binding growth factors family.
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分子量
- 36 kDa
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基因ID
- 2246
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UniProt
- P05230
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途径
- RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway
抗原
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