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Myeloperoxidase 抗体 (AA 406-745)

Name: Myeloperoxidase 抗体 (AA 406-745)
SKU: ABIN3042368
Availability: OutOfStock

MPO 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated

Anti-Myeloperoxidase Picoband antibody, All lanes: Anti- Myeloperoxidase at 0. (Myeloperoxidase 抗体 (AA 406-745))

Anti-Myeloperoxidase Picoband antibody, IHC(P): Mouse Spleen Tissue (Myeloperoxidase 抗体 (AA 406-745))

IHC

Anti-Myeloperoxidase Picoband antibody, IHC(P): Rat Spleen Tissue (Myeloperoxidase 抗体 (AA 406-745))

IHC

Anti-Myeloperoxidase Picoband antibody, IHC(P): Human Appendicitis Tissue (Myeloperoxidase 抗体 (AA 406-745))

IHC

4 images

(4 references)

产品编号 ABIN3042368

发货至: 中国

Datasheet as PDF

抗原 See all Myeloperoxidase (MPO) 抗体

Myeloperoxidase (MPO)
抗原表位
15

13

11

10

10

9

8

4

3

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 406-745
适用
157

60

52

4

3

1

1

1

1

1
人
宿主
125

64

1

1

1
兔
Compatible Secondaries
克隆类型
113

79
多克隆
标记
93

26

22

8

7

6

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
This Myeloperoxidase antibody is un-conjugated
应用范围
102

77

60

56

34

26

26

19

15

13

13

12

10

7

6

5

2

2

2

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

原理

Anti-Myeloperoxidase/MPO Antibody Picoband®

交叉反应（详细）

No cross-reactivity with other proteins

产品特性

Anti-Myeloperoxidase/MPO Antibody Picoband® (ABIN3042368). Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

纯化方法

Immunogen affinity purified.

免疫原

E.coli-derived human Myeloperoxidase recombinant protein (Position:S406-S745). Human Myeloperoxidase shares 90% amino acid (aa) sequence identity with mouse Myeloperoxidase.

亚型

IgG

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MPO 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

Western blot, 0.1-0.5 μg/mL, Human
Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/mL, Human
Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human
1. Klebanoff, S. J. : Myeloperoxidase. Proc. Assoc. Am. Phys. 111: 383-389, 1999. 2. Murao, S.-I., Stevens, F. J., Ito, A., Huberman, E. : Myeloperoxidase: a myeloid cell nuclear antigen with DNA-binding properties. Proc. Nat. Acad. Sci. 85: 1232-1236, 1988. 3. Nauseef, W. M., Olsson, I., Arnljots, K. : Biosynthesis and processing of myeloperoxidase--a marker for myeloid cell differentiation. Europ. J. Haemat. 40: 97-110, 1988.

说明

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

限制

仅限研究用
状态

Lyophilized

溶解方式

Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

浓度

500 μg/mL

缓冲液

Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C,-20 °C

储存方法

Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
Wei, Kong, Li, Guan, Wang, Miao: "Nicotinamide mononucleotide attenuates brain injury after intracerebral hemorrhage by activating Nrf2/HO-1 signaling pathway." in: Scientific reports, Vol. 7, Issue 1, pp. 717, (2018) (PubMed).

Xu, Zhang, He, Li, Gao, Liu: "Lactobacillus acidophilus alleviates pouchitis after ileal pouch-anal anastomosis in rats." in: World journal of gastroenterology, Vol. 23, Issue 26, pp. 4735-4743, (2018) (PubMed).

Wang, Liu, Liu, Wang, Fan, Ma, Jin, Xiang, Huang, Zhang, Xu, Yin, He: "Interleukin-17A Aggravates Middle Ear Injury Induced by Streptococcus pneumoniae through the p38 Mitogen-Activated Protein Kinase Signaling Pathway." in: Infection and immunity, Vol. 85, Issue 10, (2017) (PubMed).

Yu, Chen, Wang, Kuang, Liu, Zhang, Du: "Neuroprotective effect of kaempferol glycosides against brain injury and neuroinflammation by inhibiting the activation of NF-?B and STAT3 in transient focal stroke." in: PLoS ONE, Vol. 8, Issue 2, pp. e55839, (2013) (PubMed).
抗原

Myeloperoxidase (MPO)

别名

MPO (MPO 产品)

背景

Synonyms: Myeloperoxidase,MPO,1.11.2.2,Myeloperoxidase,89 kDa myeloperoxidase,84 kDa myeloperoxidase,Myeloperoxidase light chain,Myeloperoxidase heavy chain,MPO,
Tissue Specificity: Mast cells in lung, heart, skin and placenta. Expressed in both normal skin and in urticaria pigmentosa lesions. .
Background: Myeloperoxidase (MPO) is a mammalian phagocyte hemoprotein thought to primarily mediate host defense reactions. It is abundantly expressed in neutrophils and secreted during their activation. Myeloperoxidase is part of the host defense system of human polymorphonuclear leukocytes, responsible for microbicidal activity against a wide range of organisms. It is located in the nucleus as well as in the cytoplasm. Intranuclear MPO may help to protect DNA against damage resulting from oxygen radicals produced during myeloid cell maturation and function. The standard product used in this kit is the product of gene recombination, consisting of 697 (A49-S745) amino acids with the molecular mass of 80KDa.
Sequence Similarities: Belongs to the peroxidase family. XPO subfamily.

分子量

60-65 kDa, 80-90 kDa

基因ID

4353

UniProt

P05164

途径

Chromatin Binding