MICB 抗体 (N-Term)
Quick Overview for MICB 抗体 (N-Term) (ABIN3042366)
抗原
See all MICB 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-48, N-Term
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原理
- Anti-MICB Antibody Picoband®
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序列
- AEPHSLRYNL MVLSQDESVQ SGFLAE
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交叉反应 （详细）
- No cross-reactivity with other proteins
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产品特性
- Anti-MICB Antibody Picoband® (ABIN3042366). Tested in Flow Cytometry, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the N-terminus of human MICB.
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亚型
- IgG
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anti-MHC Class I Polypeptide-Related Sequence B (MICB) (AA 1-340) antibody
MICB 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-MHC Class I Polypeptide-Related Sequence B (MICB) (AA 1-340) antibodyMICB 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-MHC Class I Polypeptide-Related Sequence B (MICB) antibodyMICB 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal B-D54 unconjugated
anti-MHC Class I Polypeptide-Related Sequence B (MICB) (AA 23-309) antibodyMICB 适用: 人 ELISA, FACS 宿主: 兔 Monoclonal DM168 unconjugated
anti-MHC Class I Polypeptide-Related Sequence B (MICB) (AA 23-108) antibodyMICB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western blot, 0.1-0.5 μg/mL, Human, Mouse
Flow Cytometry(Fixed), 1-3 μg/1x106 cells, Human
1. Bahram S, Bresnahan M, Geraghty DE, Spies T (Aug 1994). "A second lineage of mammalian major histocompatibility complex class I genes". Proc Natl Acad Sci U S A 91 (14): 6259-63. 2. "Entrez Gene: MICB MHC class I polypeptide-related sequence B". 3. Leelayuwat C, Townend DC, Degli-Esposti MA et al. (1994). "A new polymorphic and multicopy MHC gene family related to nonmammalian class I.".Immunogenetics 40 (5): 339-51. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- MICB (MHC Class I Polypeptide-Related Sequence B (MICB))
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别名
- MICB
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背景
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Synonyms: MHC class I polypeptide-related sequence B,MIC-B,MICB ,PERB11.2 ,
Tissue Specificity: Widely expressed with the exception of the central nervous system where it is absent. Expressed in many, but not all, epithelial tumors of lung, breast, kidney, ovary, prostate and colon. In hepatocellular carcinomas, expressed in tumor cells but not in surrounding non-cancerous tissue. .
Background: MHC class I polypeptide-related sequence B is a protein that in humans is encoded by the MICB gene. This gene encodes a heavily glycosylated protein which is a ligand for the NKG2D type II receptor. Binding of the ligand activates the cytolytic response of natural killer (NK) cells, CD8 alphabeta T cells, and gammadelta T cells which express the receptor. This protein is stress-induced and is similar to MHC class I molecules, however, it does not associate with beta-2-microglobulin or bind peptides. Alternative splicing results in multiple transcript variants.
Sequence Similarities: Belongs to the MHC class I family. MIC subfamily.
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分子量
- 60-65 kDa
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基因ID
- 4277
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UniProt
- Q29980
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途径
- Human Leukocyte Antigen (HLA) in Adaptive Immune Response
抗原
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