Vitronectin 抗体 (C-Term)
Quick Overview for Vitronectin 抗体 (C-Term) (ABIN3042327)
抗原
See all Vitronectin (VTN) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 446-472, C-Term
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原理
- Anti-Vitronectin/VTN Antibody Picoband®
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序列
- RVNLRTRRVD TVDPPYPRSI AQYWLGC
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交叉反应 (详细)
- No cross-reactivity with other proteins
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产品特性
- Anti-Vitronectin/VTN Antibody Picoband® (ABIN3042327). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.
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纯化方法
- Immunogen affinity purified.
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免疫原
- A synthetic peptide corresponding to a sequence at the C-terminus of human Vitronectin, different from the related mouse sequence by two amino acids.
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亚型
- IgG
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应用备注
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Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
1. "Entrez Gene: M Vitronectin". 2. Jenne D, Stanley KK (October 1987). "Nucleotide sequence and organization of the human S-protein gene: repeating peptide motifs in the "pexin" family and a model for their evolution". Biochemistry 26 (21): 6735-42. 3. Preissner KT, Seiffert D (January 1998)."Role of vitronectin and its receptors in haemostasis and vascular remodeling" (&NDASH, SCHOLAR SEARCH). Thromb. Res. 89(1): 1-21. -
说明
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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浓度
- 500 μg/mL
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缓冲液
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C,-20 °C
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储存方法
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).
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Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).
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- Vitronectin (VTN)
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别名
- VTN
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背景
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Synonyms: Vitronectin,VN,S-protein,Serum-spreading factor,V75,Vitronectin V65 subunit,Vitronectin V10 subunit,Somatomedin-B,VTN,
Tissue Specificity: Plasma.
Background: Vitronectin, also known as VTN, is a protein that in humans is encoded by the VTN gene. The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Also vitronectin serves to regulate proteolysis initiated by plasminogen activation. In addition, vitronectin is a component of platelets and is, thus, involved in hemostasis.
Sequence Similarities: Contains 4 hemopexin repeats.
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分子量
- 54 kDa
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基因ID
- 7448
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UniProt
- P04004
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途径
- Autophagy, Smooth Muscle Cell Migration
抗原
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