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Vitronectin 抗体 (C-Term)

This anti-Vitronectin antibody is a 兔 多克隆 antibody detecting Vitronectin in WB 和 IHC. Suitable for 人, 小鼠 和 大鼠. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN3042327
发货至: 中国

Quick Overview for Vitronectin 抗体 (C-Term) (ABIN3042327)

抗原

See all Vitronectin (VTN) 抗体
Vitronectin (VTN)

适用

  • 111
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人, 小鼠, 大鼠

宿主

  • 107
  • 26
  • 4
  • 1
  • 1

克隆类型

  • 104
  • 35
多克隆

标记

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This Vitronectin antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

    • 15
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    AA 446-472, C-Term

    原理

    Anti-Vitronectin/VTN Antibody Picoband®

    序列

    RVNLRTRRVD TVDPPYPRSI AQYWLGC

    交叉反应 (详细)

    No cross-reactivity with other proteins

    产品特性

    Anti-Vitronectin/VTN Antibody Picoband® (ABIN3042327). Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    纯化方法

    Immunogen affinity purified.

    免疫原

    A synthetic peptide corresponding to a sequence at the C-terminus of human Vitronectin, different from the related mouse sequence by two amino acids.

    亚型

    IgG
  • 应用备注

    Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
    1. "Entrez Gene: M Vitronectin". 2. Jenne D, Stanley KK (October 1987). "Nucleotide sequence and organization of the human S-protein gene: repeating peptide motifs in the "pexin" family and a model for their evolution". Biochemistry 26 (21): 6735-42. 3. Preissner KT, Seiffert D (January 1998)."Role of vitronectin and its receptors in haemostasis and vascular remodeling" (&NDASH, SCHOLAR SEARCH). Thromb. Res. 89(1): 1-21.

    说明

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    浓度

    500 μg/mL

    缓冲液

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C,-20 °C

    储存方法

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Zeng, Ma, Chen, Qiu, Wu, Ling, Zeng: "Autocrine fibronectin from differentiating mesenchymal stem cells induces the neurite elongation in vitro and promotes nerve fiber regeneration in transected spinal cord injury." in: Journal of biomedical materials research. Part A, Vol. 104, Issue 8, pp. 1902-11, (2017) (PubMed).

  • 抗原

    Vitronectin (VTN)

    别名

    VTN

    背景

    Synonyms: Vitronectin,VN,S-protein,Serum-spreading factor,V75,Vitronectin V65 subunit,Vitronectin V10 subunit,Somatomedin-B,VTN,

    Tissue Specificity: Plasma.

    Background: Vitronectin, also known as VTN, is a protein that in humans is encoded by the VTN gene. The protein encoded by this gene is a member of the pexin family. It is found in serum and tissues and promotes cell adhesion and spreading, inhibits the membrane-damaging effect of the terminal cytolytic complement pathway, and binds to several serpin serine protease inhibitors. It is a secreted protein and exists in either a single chain form or a clipped, two chain form held together by a disulfide bond. Also vitronectin serves to regulate proteolysis initiated by plasminogen activation. In addition, vitronectin is a component of platelets and is, thus, involved in hemostasis.

    Sequence Similarities: Contains 4 hemopexin repeats.

    分子量

    54 kDa

    基因ID

    7448

    UniProt

    P04004

    途径

    Autophagy, Smooth Muscle Cell Migration
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