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TUBA1B 抗体 (Biotin)

TUBA1B 适用: Pig WB 宿主: 小鼠 Monoclonal TU-01 Biotin
产品编号 ABIN303511
发货至: 中国
  • 抗原 See all TUBA1B 抗体
    TUBA1B (Tubulin, alpha 1B (TUBA1B))
    适用
    • 45
    • 25
    • 23
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Pig
    宿主
    • 36
    • 11
    • 1
    小鼠
    克隆类型
    • 34
    • 14
    单克隆
    标记
    • 26
    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TUBA1B antibody is conjugated to Biotin
    应用范围
    • 43
    • 20
    • 17
    • 14
    • 13
    • 10
    • 7
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    特异性
    The antibody TU-01 recognizes the defined epitope (aa 65-97) on N-terminal structural domain of alpha-tubulin.
    免疫原
    Fraction of tubulin purified from porcine brain by two cycles of polymerization - depolymerization.
    克隆位点
    TU-01
    亚型
    IgG1
    Top Product
    Discover our top product TUBA1B Primary Antibody
  • 应用备注
    Western Blotting (1/1000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS, pH ~7.4, 15 mM Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • 抗原
    TUBA1B (Tubulin, alpha 1B (TUBA1B))
    别名
    alpha Tubulin / TUBA1B (TUBA1B 产品)
    别名
    RGD1565476 antibody, K-ALPHA-1 antibody, cb944 antibody, fb22g06 antibody, tuba1 antibody, wu:fb22g06 antibody, Tuba2 antibody, TUBA3 antibody, k-alpha-1 antibody, tuba antibody, Calpha1 antibody, Tuba1 antibody, TUBA1B antibody, tubulin, alpha 1B antibody, tubulin alpha 1b antibody, tubulin, alpha 1b antibody, tubulin alpha 1b L homeolog antibody, tubulin alpha-1B chain antibody, Tubulin alpha-1B chain antibody, Tuba1b antibody, TUBA1B antibody, tuba1b antibody, tuba1b.L antibody, LOC100445003 antibody, LOC102178700 antibody
    背景
    The microtubules are intracellular dynamic polymers made up of evolutionarily conserved polymorphic alpha/beta-tubulin heterodimers and a large number of microtubule-associated proteins (MAPs). The microtubules consist of 13 protofilaments and have an outer diameter 25 nm. Microtubules have their intrinsic polarity, highly dynamic plus ends and less dynamic minus ends. Microtubules are required for vital processes in eukaryotic cells including mitosis, meiosis, maintenance of cell shape and intracellular transport. Microtubules are also necessary for movement of cells by means of flagella and cilia. In mammalian tissue culture cells microtubules have their minus ends anchored in microtubule organizing centers (MTOCs).The GTP (guanosintriphosphate) molecule is an essential for tubulin heterodimer to associate with other heterodimers to form microtubule. In vivo, microtubule dynamics vary considerably. Microtubule polymerization is reversible and a populations of microtubules in cells are on their minus ends either growing or shortening - this phenomenon is called dynamic instability of microtubules. On a practical level, microtubules can easily be stabilized by the addition of non-hydrolysable analogues of GTP (eg. GMPPCP) or more commonly by anti-cancer drugs such as Taxol. Taxol stabilizes microtubules at room temperature for many hours. Using limited proteolysis by enzymes both tubulin subunits can be divided into N-terminal and C-terminal structural domains. The alpha-tubulin (relative molecular weight around 50 kDa) is globular protein that exists in cells as part of soluble alpha/beta-tubulin dimer or it is polymerized into microtubules. In different species it is coded by multiple tubulin genes that form tubulin classes (in human 6 genes). Expressed tubulin genes are named tubulin isotypes. Some of the tubulin isotypes are expressed ubiquitously, while some have more restricted tissue expression. Alpha-tubulin is also subject of numerous post-translational modifications. Tubulin isotypes and their posttranslational modifications are responsible for multiple tubulin charge variants - tubulin isoforms. Heterogeneity of alpha-tubulin is concentrated in C-terminal structural domain.Synonyms: Alpha-tubulin ubiquitous, Tubulin K-alpha-1, Tubulin alpha-1B chain, Tubulin alpha-ubiquitous chain
    基因ID
    10376
    NCBI登录号
    NP_006073
    UniProt
    P68363
    途径
    Microtubule Dynamics, M Phase
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