DCLRE1C 抗体 (AA 482-495)
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Quick Overview for DCLRE1C 抗体 (AA 482-495) (ABIN303343)
抗原
See all DCLRE1C 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 482-495
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic Peptide corresponding to aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross- link repair 1C).
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应用备注
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Immunohistochemistry on Paraffin Sections (1.25-2.5 μg/mL). Western Blot (1/500-1/2000). ELISA (1/10000-1/20000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid cycles of freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at-20 °C. Dilute only prior to immediate use.
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- DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))
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别名
- Artemis
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背景
- Human Artemis is a newly identified 78.4 kDa, novel DNA double-strand break repair/v(d)j recombination protein. This gene is located at human chromosome 10. Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C
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基因ID
- 64421
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NCBI登录号
- NP_001029027
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UniProt
- Q96SD1
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途径
- DNA Damage Repair
抗原
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