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DCLRE1C 抗体 (AA 482-495)

This 山羊 多克隆 antibody specifically detects DCLRE1C in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人.
产品编号 ABIN303343
发货至: 中国
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Quick Overview for DCLRE1C 抗体 (AA 482-495) (ABIN303343)

抗原

See all DCLRE1C 抗体
DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

适用

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宿主

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山羊

克隆类型

  • 60
多克隆

标记

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This DCLRE1C antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    AA 482-495

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Synthetic Peptide corresponding to aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross- link repair 1C).
  • 应用备注

    Immunohistochemistry on Paraffin Sections (1.25-2.5 μg/mL). Western Blot (1/500-1/2000). ELISA (1/10000-1/20000).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid cycles of freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at-20 °C. Dilute only prior to immediate use.
  • 抗原

    DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

    别名

    Artemis

    背景

    Human Artemis is a newly identified 78.4 kDa, novel DNA double-strand break repair/v(d)j recombination protein. This gene is located at human chromosome 10. Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C

    基因ID

    64421

    NCBI登录号

    NP_001029027

    UniProt

    Q96SD1

    途径

    DNA Damage Repair
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