TLR5 抗体 (Center)
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北京 101111
Quick Overview for TLR5 抗体 (Center) (ABIN303300)
抗原
See all TLR5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应 （详细）
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic Peptide corresponding to 16 amino acids near the center of human TLR5.
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anti-Toll-Like Receptor 5 (TLR5) (AA 325-644) antibody
TLR5 适用: 大鼠 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 303-514) antibodyTLR5 适用: 人 WB, ELISA, ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal 8-1# unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 682-850) antibodyTLR5 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 700-800) antibodyTLR5 适用: 人, 小鼠 WB, IHC, FACS, IHC (fro) 宿主: 小鼠 Monoclonal 19D759-2 unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 701-810) antibodyTLR5 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 46-205) antibodyTLR5 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Toll-Like Receptor 5 (TLR5) (AA 693-858) antibodyTLR5 适用: 人 WB, IHC, ICC, IP 宿主: 小鼠 Monoclonal C6 unconjugated
anti-Toll-Like Receptor 5 (TLR5) (C-Term) antibodyTLR5 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
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Western Blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL. This TLR5 antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. Species Reactivity: Tested: Human. Expected from sequence similarity: Mouse and Rat. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
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- TLR5 (Toll-Like Receptor 5 (TLR5))
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别名
- TLR5
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背景
- The Toll like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules and could constitute an important and unrecognized component of innate immunity in humans. The TRL family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition. TLRs characterized so far activate the MyD88/interleukin 1 receptor-associated kinase (IRAK) signaling pathway. Toll-like receptor 5 (TLR5) expression is upregulated following exposure to bacteria or to the TLR5 agonist, flagellin. Gram-negative bacteria, stimulate monocyte/macrophage cells in a TLR5-specific, CD14-independent manner. The TLR5 receptor thus appears to be the principal means by which the innate immune system recognizes flagellated bacterial pathogens.Synonyms: TIL3, Toll-like receptor 5, Toll/interleukin-1 receptor-like protein 3
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基因ID
- 7100
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NCBI登录号
- NP_003259
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UniProt
- O60602
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途径
- TLR signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades
抗原
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