NLRP1 抗体 (C-Term)
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Quick Overview for NLRP1 抗体 (C-Term) (ABIN303286)
抗原
See all NLRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects NALP1 (CARD7).
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纯化方法
- IgG Fractionation.
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免疫原
- Synthetic Peptide corresponding to 13 amino acids near the carboxy-terminus of human NALP1
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应用备注
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Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunocytochemistry. Western Blot (1-2 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
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- NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))
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别名
- CARD7 / NLRP1
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背景
- Death Effector Filament-forming Ced 4 like Apoptosis Protein (DEFCAP) is a novel apoptotic protein of the mammalian Ced 4 family. It has two isoforms: DEFCAP-Land DEFCAP-S. The deduced amino acid sequences of these two alternately spliced isoforms only differ by 44amino acids at the C-terminus. DEFCAP contains a caspase recruitment domain (CARD), a domain that with the proper stimulation can recruit caspases to form cytoplasmic structures called death effector filaments, which in turn initiate the apoptotic signaling pathway.Synonyms: Caspase recruitment domain-containing protein 7, DEFCAP, Death effector filament-forming ced-4-like apoptosis protein, KIAA0926, LRR and PYD domains-containing protein 1, NAC, NACHT, NALP1, Nucleotide-binding domain and caspase recruitment domain
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基因ID
- 22861
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NCBI登录号
- NP_001028225
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UniProt
- Q9C000
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途径
- Positive Regulation of Endopeptidase Activity, Inflammasome
抗原
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