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NLRP1 抗体 (C-Term)

This 兔 多克隆 antibody specifically detects NLRP1 in WB, IF 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN303286
发货至: 中国
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Quick Overview for NLRP1 抗体 (C-Term) (ABIN303286)

抗原

See all NLRP1 抗体
NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

适用

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宿主

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克隆类型

  • 40
多克隆

标记

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This NLRP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    C-Term

    特异性

    This antibody detects NALP1 (CARD7).

    纯化方法

    IgG Fractionation.

    免疫原

    Synthetic Peptide corresponding to 13 amino acids near the carboxy-terminus of human NALP1
  • 应用备注

    Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Immunocytochemistry. Western Blot (1-2 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
  • 抗原

    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

    别名

    CARD7 / NLRP1

    背景

    Death Effector Filament-forming Ced 4 like Apoptosis Protein (DEFCAP) is a novel apoptotic protein of the mammalian Ced 4 family. It has two isoforms: DEFCAP-Land DEFCAP-S. The deduced amino acid sequences of these two alternately spliced isoforms only differ by 44amino acids at the C-terminus. DEFCAP contains a caspase recruitment domain (CARD), a domain that with the proper stimulation can recruit caspases to form cytoplasmic structures called death effector filaments, which in turn initiate the apoptotic signaling pathway.Synonyms: Caspase recruitment domain-containing protein 7, DEFCAP, Death effector filament-forming ced-4-like apoptosis protein, KIAA0926, LRR and PYD domains-containing protein 1, NAC, NACHT, NALP1, Nucleotide-binding domain and caspase recruitment domain

    基因ID

    22861

    NCBI登录号

    NP_001028225

    UniProt

    Q9C000

    途径

    Positive Regulation of Endopeptidase Activity, Inflammasome
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