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LAMP1 抗体 (Center)

This anti-LAMP1 antibody is a 兔 多克隆 antibody detecting LAMP1 in WB, IF 和 IHC (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN303277
发货至: 中国

Quick Overview for LAMP1 抗体 (Center) (ABIN303277)

抗原

See all LAMP1 抗体
LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This LAMP1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
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    Center

    特异性

    Recognizes Lysosome-associated Membrane Glycoprotein 1 (LAMP1).

    交叉反应 (详细)

    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Synthetic Peptide corresponding to 15 amino acid peptide from near the center of Human LAMP-1.
  • 应用备注

    Western Blot. Immunofluorescence. Immunohistochemistry on Paraffin Sections (5 μg/mL). This LAMP1 antibody was validated for use in immunohistochemistry on a panel of 21formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigenretrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides wereincubated with biotinylated secondary antibody, followed by alkalinephosphatase-streptavidin and chromogen.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
  • 抗原

    LAMP1 (Lysosomal-Associated Membrane Protein 1 (LAMP1))

    别名

    CD107a / LAMP1

    背景

    CD107a (lysosome-associated membrane protein-1, LAMP-1), together with LAMP-2, is a major constituent of lysosomal membrane, 1-2 % of total CD107a is found also on the plasma membrane. The LAMP proteins are involved in lysosome biogenesis and are required for fusion of lysosomes with phagosomes. Increased CD107a immunoreactivity is observed in neurones, and in glial cells surrounding senile plaques in Alzheimers disease cases and is localized mainly in medullary epithelial cells, single macrophages and lymphocytes in acute thymic involution. CD107a is a good marker of mast cell activation.Synonyms: CD107 Antigen-like Family Member A, LAMP-1, LAMPA, LGP120, Lysosome-associated membrane glycoprotein 1

    基因ID

    3916

    NCBI登录号

    NP_005552

    UniProt

    P11279

    途径

    Autophagy
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