IL23A 抗体 (N-Term)
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Quick Overview for IL23A 抗体 (N-Term) (ABIN303269)
抗原
See all IL23A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody recognises Interleukin-23 Subunit alpha (SGRF).
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纯化方法
- Immunoaffinity Chromatography.
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免疫原
- Synthetic Peptide corresponding to 16 amino acid peptide from near the amino terminus of human IL-23.
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anti-Interleukin 23, alpha subunit p19 (IL23A) (C-Term) antibody
IL23A 适用: 人 WB, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C8 unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 20-189) antibodyIL23A 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (N-Term) antibodyIL23A 适用: 人, 小鼠 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 33-67) antibodyIL23A 适用: 人, 小鼠 WB, FACS 宿主: 兔 Polyclonal RB56752 unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 20-155) antibodyIL23A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) (AA 1-189) antibodyIL23A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 23, alpha subunit p19 (IL23A) antibodyIL23A 适用: 人 WB, ELISA 宿主: 兔 Monoclonal 1F6 unconjugated Recombinant Antibody
anti-Interleukin 23, alpha subunit p19 (IL23A) antibodyIL23A 适用: 人 WB, ELISA 宿主: 大鼠 Monoclonal I 178G unconjugated
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应用备注
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Immunohistochemistry on Paraffin Sections (2.5 μg/mL). Western Blot (1-2 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- Phosphate Buffered Saline PBS containing 0.02 % Sodium Azide as preservative.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.
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- IL23A (Interleukin 23, alpha subunit p19 (IL23A))
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别名
- Interleukin-23 alpha / IL23A
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背景
- IL23 is composed of the IL12 p40 subunit and a p19 subunit (IL23P19 or IL23A). The p19 subunit shares sequence similarity with IL6 subfamily members and is distantly related to the p35 subunit of IL12. It shows no biological activity by itself, instead, it combines with the p40 subunit of IL12 to form a biologically active, composite cytokine, IL23. IL12 and IL23 are molecules mainly produced by activated accessory and antigen-presenting cells. Both IL23 and IL12 can activate the transcription activator STAT4. In contrast to IL12, which acts mainly on naive CD4(+) T cells, IL23 preferentially acts on memory CD4(+) T cells. IL12 used to be thought to be the prime-regulator of TH1 development but upon discovery of IL23 and the fact that the large subunit of IL23 is shared by IL12, it is now thought that the features attributed to IL12 and TH1 development in inflammation are, in fact, dependent on IL23 rather than IL12. IL23 is implicated in protective and autoimmune responses.Synonyms: IL-23 subunit alpha, IL-23p19, Interleukin-23 subunit p19, SGRF
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基因ID
- 51561
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NCBI登录号
- NP_057668
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UniProt
- Q9NPF7
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途径
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation
抗原
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