PKC iota 抗体 (AA 21-214)
-
- 抗原 See all PKC iota (PRKCI) 抗体
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
-
抗原表位
- AA 21-214
-
适用
- 人, 小鼠, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PKC iota antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 纯化方法
- Antigen affinity
- 免疫原
- Human partial recombinant protein (AA 21-214) was used as the immunogen for this PKC iota antibody.
- 亚型
- IgG
- Top Product
- Discover our top product PRKCI Primary Antibody
-
anti-Protein Kinase C, iota (PRKCI) (AA 375-596) antibody
PRKCI 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 1-587) antibodyPRKCI 适用: 人 WB, ELISA, IF, RNAi 宿主: 小鼠 Monoclonal 1G11 unconjugated
anti-Protein Kinase C, iota (PRKCI) (N-Term) antibodyPRKCI 适用: 人, 小鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 21-214) antibodyPRKCI 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 1-100) antibodyPRKCI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1A10 unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 176-207), (N-Term) antibodyPRKCI 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB01026 unconjugated
anti-Protein Kinase C, iota (PRKCI) (Internal Region) antibodyPRKCI 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, iota (PRKCI) (AA 215-264) antibodyPRKCI 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Protein Kinase C, iota (PRKCI) (Middle Region) antibodyPRKCI 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
-
- 应用备注
- The stated application concentrations are suggested starting amounts. Titration of the PKC iota antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
- 限制
- 仅限研究用
-
- 缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
- 储存条件
- -20 °C
- 储存方法
- After reconstitution, the PKC iota antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
- 抗原
- PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
- 别名
- PKC iota (PRKCI 产品)
- 别名
- DXS1179E antibody, PKCI antibody, nPKC-iota antibody, aPKC[l] antibody, hal antibody, has antibody, PRKCI antibody, PKC antibody, 2310021H13Rik antibody, AI427505 antibody, PKClambda antibody, Pkci antibody, Pkcl antibody, Prkcl antibody, aPKClambda antibody, mKIAA4165 antibody, protein kinase C iota antibody, protein kinase C, iota antibody, PRKCI antibody, prkci antibody, Prkci antibody
- 背景
- Protein kinase C iota, also called PKCI, is an enzyme that in humans is encoded by the PRKCI gene. This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where it phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. PRKCI is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. It is also a hedgehog target gene that forms a positive feedback loop with GLI and exists at increased levels in basal cell carcinomas.
- 基因ID
- 5584
- 途径
- Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
-
