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PLGF 抗体 (C-Term)

This anti-PLGF antibody is a 兔 多克隆 antibody detecting PLGF in WB. Suitable for 人.
产品编号 ABIN3032240
发货至: 中国

Quick Overview for PLGF 抗体 (C-Term) (ABIN3032240)

抗原

See all PLGF (PGF) 抗体
PLGF (PGF) (Placenta Growth Factor (PGF))

适用

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宿主

  • 107
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克隆类型

  • 96
  • 45
多克隆

标记

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This PLGF antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of human PLGF (REKMKPERCGDAVPRR) was used as the immunogen for this PLGF antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the PLGF antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the PLGF antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    PLGF (PGF) (Placenta Growth Factor (PGF))

    别名

    PLGF

    背景

    Placental growth factor(PGF, also known as PLGF) codes for an angiogenic factor expressed in placental tissue that is similar to vascular permeability factor/vascular endothelial growth factor(VPF/VEGF). It is a glycosylated dimeric secreted protein able to stimulate endothelial cell growth in vitro. PGF is located on chromosome 14 and has been conserved in evolution. It belongs to the family of vascular endothelial growth factors(VEGFs) and binds to the flt-1 VEGF receptor. PLGF-2, which is a PLGF isoform, binds neuropilin-1 and 2 in a heparin-dependent manner. PGF regulates inter- and intra molecular cross talk between the VEGF RTKs Flt1 and Flk1 and stimulates the phosphorylation of specific Flt1 tyrosine residues and the expression of distinct downstream target genes. Moreover, it plays an important role in pathological angiogenic events and with exerting its biological activities through binding to VEGFR1.

    UniProt

    P49763

    途径

    VEGFR1 Specific Signals
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