Peroxiredoxin 3 抗体 (AA 239-256)
Quick Overview for Peroxiredoxin 3 抗体 (AA 239-256) (ABIN3032188)
抗原
See all Peroxiredoxin 3 (PRDX3) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 239-256
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纯化方法
- Antigen affinity
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免疫原
- Amino acids 239-256 (TIKPSPAASKEYFQKVNQ-human) were used as the immunogen for this Peroxiredoxin 3 antibody.
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亚型
- IgG
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应用备注
- Titration of the Peroxiredoxin 3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL
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限制
- 仅限研究用
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缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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储存条件
- -20 °C
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储存方法
- The lyophilized Peroxiredoxin 3 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- Peroxiredoxin 3 (PRDX3)
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背景
- Peroxiredoxin 3 is a mitochondrial protein belonging to the AhpC/TSA family. Expression of PRDX3 is induced by MYC and is reduced in c-myc -/- cells. Chromatin immunoprecipitation analysis spanning the entire PRDX3 genomic sequence revealed that MYC binds preferentially to a 930-bp region surrounding exon 1. Results using mitochondria-specific fluorescent probes demonstrated that Peroxiredoxin 3 is essential for maintaining mitochondrial mass and membrane potential in transformed rat and human cells.
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UniProt
- P30048
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途径
- Ribonucleoside Biosynthetic Process, Methionine Biosynthetic Process
抗原
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