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Patched 2 抗体 (C-Term)

This anti-Patched 2 antibody (ABIN3032167) is a Rabbit Polyclonal antibody detecting Patched 2 in WB. Suitable for Human, Mouse.
产品编号 ABIN3032167
发货至: 中国

Quick Overview for Patched 2 抗体 (C-Term) (ABIN3032167)

抗原

See all Patched 2 (PTCH2) 抗体
Patched 2 (PTCH2)

适用

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人, 小鼠

宿主

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克隆类型

  • 15
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多克隆

标记

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This Patched 2 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    纯化方法

    Antigen affinity

    免疫原

    An amino acid sequence from the C-terminus of human Patched 2 (WLHDKYDTTGENLRIPP) was used as the immunogen for this PTCH2 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the PTCH2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the PTCH2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Patched 2 (PTCH2)

    别名

    PTCH2 (Patched 2)

    背景

    PTCH2 (Patched 2), also known as PTC2, encodes a 1.203-amino acid putative transmembrane protein that is highly homologous to the PTCH product. The Patched-hedgehog signaling pathway is involved in establishing segment polarity and the anterior-posterior orientation of a number of developing appendages. The pathway is conserved from fly to vertebrates and has been implicated in a number of human neoplasms and developmental syndromes. Mutations in the human Patched gene are the basis of the nevoid basal cell carcinoma syndrome. With age, homozygous mutant male mice developed skin lesions consisting of alopecia and epidermal hyperplasia, suggesting a role for PTCH2 in adult epidermal homeostasis via Shh signaling.

    UniProt

    Q9Y6C5

    途径

    Hedgehog Signaling
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