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CASP5 抗体 (Center)

This 兔 多克隆 antibody specifically detects CASP5 in WB, IF 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN303202
发货至: 中国
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北京 101111
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Beijing Economic Technological Development Area
Room 801-803
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Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CASP5 抗体 (Center) (ABIN303202)

抗原

See all CASP5 抗体
CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

适用

  • 55
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宿主

  • 52
  • 3

克隆类型

  • 34
  • 21
多克隆

标记

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This CASP5 antibody is un-conjugated

应用范围

  • 37
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  • 5
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  • 1
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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
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    • 1
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    Center

    纯化方法

    Immunoaffinity Chromatography.

    免疫原

    Synthetic peptide corresponding to 14 amino acid peptide from the center of human Caspase-5.
  • 应用备注

    Immunohistochemistry on Paraffin Sections (5 μg/mL). Immunocytochemistry. Western Blot (0.5-1 μg/mL).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    Phosphate Buffered Saline PBS, containing 0.02 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer. Dilute only prior to immediate use.
  • 抗原

    CASP5 (Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

    别名

    Caspase-5

    背景

    Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12. Activation of these caspases results in the cleavage and activation of proinflammatory cytokines such as IL-1b and IL-18. Caspase-5 can interact with caspase-1, both are constituents of the NALP1 inflammasome, a complex that can trigger the cleavage of pro-IL-1b. Expression of caspase-5 can be regulated by lipopolysaccharide (LPS) and IFN-g.Synonyms: CASP-5, CASP5, ICE(rel)-III, ICH-3 protease, ICH3, TY protease

    基因ID

    838

    NCBI登录号

    NP_001129581

    UniProt

    P51878

    途径

    Inflammasome
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