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MME 抗体 (AA 52-750)

MME 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

Western blot testing of CD10 antibody and Lane 1: rat kidney; 2: (r) brain; 3: (r) liver; 4: human placenta; 5: (h) HeLa; 6: (h) Jurkat; 7: (h) Raji; 8: (h) 293T lysate; Routinely visualized at ~100KD (MME 抗体 (AA 52-750))

IHC-P: CD10 antibody testing of human B-lymphocyte cancer tissue (MME 抗体 (AA 52-750))

IHC-P: CD10 antibody testing of mouse kidney tissue (MME 抗体 (AA 52-750))

IHC-P: CD10 antibody testing of mouse spleen tissue (MME 抗体 (AA 52-750))

Western blot testing of CD10 antibody and Lane 1: rat kidney (MME 抗体 (AA 52-750))

IHC-P: CD10 antibody testing of mouse spleen tissue (MME 抗体 (AA 52-750))

IHC-P: CD10 antibody testing of rat spleen tissue (MME 抗体 (AA 52-750))

IHC-P: CD10 antibody testing of mouse kidney tissue (MME 抗体 (AA 52-750))

8 images

产品编号 ABIN3031745

发货至: 中国

Datasheet as PDF

抗原 See all MME 抗体

MME (Membrane Metallo-Endopeptidase (MME))
抗原表位
16

14

10

8

8

7

7

7

7

6

5

4

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 52-750
适用
207

58

50

3

2

2

2

2

2

1

1

1

1
人, 小鼠, 大鼠
宿主
111

102

2
兔
Compatible Secondaries
克隆类型
109

105

2
多克隆
标记
108

19

18

13

9

6

4

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
This MME antibody is un-conjugated
应用范围
132

97

78

67

35

28

22

20

13

13

10

8

6

5

5

3

2

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

纯化方法

Antigen affinity

免疫原

Human partial recombinant protein (AA 52-750) was used as the immunogen for this CD10 antibody.

亚型

IgG

Top Product

Discover our top product MME Primary Antibody
anti-Membrane Metallo-Endopeptidase (MME) (AA 52-352) antibody
MME 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-246) antibody
MME 适用: 人 WB, IHC, ELISA 宿主: 小鼠 Monoclonal 7D4B1 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 501-600) antibody
MME 适用: 人, 小鼠, 大鼠 FACS, WB, ELISA, IHC (p), ICC, IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 382-538) antibody
MME 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal MME-1870 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 286-428) antibody
MME 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 297-483) antibody
MME 适用: 人 WB, IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal MME-1892 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) antibody (FITC)
MME 适用: 人 FACS 宿主: 小鼠 Monoclonal MEM-78 FITC

anti-Membrane Metallo-Endopeptidase (MME) (AA 549-750) antibody
MME 适用: 人 FACS, WB, IHC, ELISA, ICC, Neut 宿主: 小鼠 Monoclonal 6G12E12 unconjugated

anti-Membrane Metallo-Endopeptidase (MME) (AA 52-750) antibody
MME 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

应用备注

The stated application concentrations are suggested starting amounts. Titration of the CD10 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

限制

仅限研究用
缓冲液

0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

储存条件

-20 °C

储存方法

After reconstitution, the CD10 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
抗原

MME (Membrane Metallo-Endopeptidase (MME))

别名

CD10 (MME 产品)

别名

CALLA antibody, CD10 antibody, NEP antibody, SFE antibody, 6030454K05Rik antibody, C85356 antibody, Nep antibody, neprilysin antibody, membrane metalloendopeptidase antibody, membrane metallo endopeptidase antibody, membrane metallo-endopeptidase antibody, MME antibody, Mme antibody

物质类

Chemical

背景

CD10, also known as membrane metallo-endopeptidase, neutral endopeptidase (NEP), Neprilysin, or common acute lymphoblastic leukemia antigen (CALLA), is a zinc-dependent metalloprotease enzyme that degrades a number of small secreted peptides, most notably theamyloid beta peptide whose abnormal misfolding and aggregation in neural tissue has been implicated as a cause of Alzheimers disease. This gene is localized to human chromosome 3 by study of somatic cell hybrids and regionalized the location to 3q21-q27 by in situ hybridization. By cDNA transfection analysis, CD10 is confirmed as a functional neutral endopeptidase of the type that has previously been called enkephalinase. CD10 has also been called atriopeptidase. Atriopeptidase specifically degrades atrial natriuretic factor. A specific enzyme inhibitor was developed and reported that it had effects similar to those of low-dose ANF infusion. These effects include diuresis, natriuresis, vasodilatation, and suppression of the renin-angiotensin-aldosterone system.

基因ID

4311

途径

RTK signaling, Peptide Hormone Metabolism, Regulation of Systemic Arterial Blood Pressure by Hormones, Smooth Muscle Cell Migration

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