Integrin beta 2 抗体 (AA 17-382)
Quick Overview for Integrin beta 2 抗体 (AA 17-382) (ABIN3031376)
抗原
See all Integrin beta 2 (ITGB2) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 17-382
-
纯化方法
- Antigen affinity
-
免疫原
- Human partial recombinant protein (AA 17-382) was used as the immunogen for this MAC-1 antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- The stated application concentrations are suggested starting amounts. Titration of the MAC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
-
限制
- 仅限研究用
-
-
-
缓冲液
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
储存条件
- -20 °C
-
储存方法
- After reconstitution, the MAC-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- Integrin beta 2 (ITGB2)
-
别名
- MAC-1
-
背景
- Macrophage-1 alpha (MAC-1) or CD11b are glycoproteins encoded by the ITGAM gene. It is mapped to 16p11.2. MAC-1 has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Additionally, it likely recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.
-
基因ID
- 3684
-
途径
- NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
抗原
-