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Integrin beta 2 抗体 (AA 17-382)

This 兔 多克隆 anti-Integrin beta 2 antibody specifically detects Integrin beta 2 in WB 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN3031376
发货至: 中国
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Quick Overview for Integrin beta 2 抗体 (AA 17-382) (ABIN3031376)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This Integrin beta 2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

    • 20
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    AA 17-382

    纯化方法

    Antigen affinity

    免疫原

    Human partial recombinant protein (AA 17-382) was used as the immunogen for this MAC-1 antibody.

    亚型

    IgG
  • 应用备注

    The stated application concentrations are suggested starting amounts. Titration of the MAC-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

    限制

    仅限研究用
  • 缓冲液

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    储存条件

    -20 °C

    储存方法

    After reconstitution, the MAC-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    MAC-1

    背景

    Macrophage-1 alpha (MAC-1) or CD11b are glycoproteins encoded by the ITGAM gene. It is mapped to 16p11.2. MAC-1 has a role in vascular repair after mechanical arterial injury. It is implicated in various adhesive interactions of monocytes, macrophages and granulocytes as well as in mediating the uptake of complement-coated particles. Additionally, it likely recognizes the R-G-D peptide in C3b, and it is also a receptor for fibrinogen, factor X and ICAM1.

    基因ID

    3684

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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